Journal article
Chemoselective deprotection and functional group interconversion of ring-fused 2N,3O-oxazolidinones of N-acetyl-d-glucosamine
Tetrahedron letters, Vol.46(40), pp.6901-6905
10/2005
DOI: 10.1016/j.tetlet.2005.08.013
Abstract
These studies describe the chemoselective deprotection of trans-fused 2N,3O-oxazolidinone derivatives of N-acetyl-β-D-glucosamine. Selective opening of the oxazolidinone ring or N-deacetylation without ring opening is demonstrated. Certain amines are shown to efficiently afford C-2 ureido sugars under mild conditions. This work demonstrates the high degree of chemoselective manipulation possible with ring-fused 2N,3O-oxazolidinone derivatives of N-acetyl-D-glucosamine. © 2005 Elsevier Ltd. All rights reserved.
Details
- Title: Subtitle
- Chemoselective deprotection and functional group interconversion of ring-fused 2N,3O-oxazolidinones of N-acetyl-d-glucosamine
- Creators
- Peng Wei - University of IowaRobert J. Kerns
- Resource Type
- Journal article
- Publication Details
- Tetrahedron letters, Vol.46(40), pp.6901-6905
- DOI
- 10.1016/j.tetlet.2005.08.013
- ISSN
- 0040-4039
- eISSN
- 1873-3581
- Language
- English
- Date published
- 10/2005
- Academic Unit
- Medicinal and Natural Products Chemistry; Pharmaceutical Sciences and Experimental Therapeutics
- Record Identifier
- 9984365893502771
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