Journal article
Chickenpox and the geniculate ganglion: facial nerve palsy, Ramsay hunt syndrome and acyclovir treatment
The Pediatric infectious disease journal, Vol.21(7), pp.615-617
2002
DOI: 10.1097/00006454-200207000-00002
PMID: 12237590
Abstract
Facial nerve palsy has long been considered to have an infectious etiology. Recent diagnostic analyses in children and adults have provided convincing evidence that reactivation of varicella-zoster virus (VZV), sometimes during infectious mononucleosis, can lead to cranial nerve VII palsy. The site of reactivation from latency is the geniculate ganglion. Virus most likely enters the ganglion during chickenpox, via the sensory branches of the facial nerve located on the ear and tongue. Retrospective reviews suggest that patients with VZV-related facial nerve palsy have poorer outcomes than other cases of Bell's palsy. Therefore treatment with acyclovir is suggested when VZV reactivation i slikely.
Details
- Title: Subtitle
- Chickenpox and the geniculate ganglion: facial nerve palsy, Ramsay hunt syndrome and acyclovir treatment
- Creators
- Charles GROSE - Divisions of Neurology and Infectious Diseases, Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, United StatesDaniel BONTHIUS - Divisions of Neurology and Infectious Diseases, Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, United StatesAdel K AFIFI - Divisions of Neurology and Infectious Diseases, Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, United States
- Resource Type
- Journal article
- Publication Details
- The Pediatric infectious disease journal, Vol.21(7), pp.615-617
- Publisher
- Lippincott
- DOI
- 10.1097/00006454-200207000-00002
- PMID
- 12237590
- ISSN
- 0891-3668
- eISSN
- 1532-0987
- Language
- English
- Date published
- 2002
- Academic Unit
- Neurology; Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
- Record Identifier
- 9984093608302771
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