Journal article
Chloriolide, a 12-membered macrolide from Chloridium virescens var. chlamydosporum (NRRL 37636)
Journal of natural products (Washington, D.C.), Vol.69(4), pp.636-639
2006
DOI: 10.1021/np0504964
PMID: 16643041
Abstract
A new 12-membered macrolide (chloriolide; 1) was obtained from solid-substrate fermentation cultures of Chloridium virescens var. chlamydosporum that was originally isolated from decayed wood. The structure of 1 was determined by analysis of ID NMR, 2D NMR, and MS data and confirmed by X-ray crystallographic analysis. The absolute configuration of 1 was assigned by application of the modified Mosher method using the (R)- and (S)-MTPA derivatives of a rearrangement product obtained under standard acylation conditions. The assignment made by analysis of the corresponding Δδ values was verified by X-ray crystallographic analysis of the (S)-MTPA derivative. © 2006 American Chemical Society and American Society of Pharmacognosy.
Details
- Title: Subtitle
- Chloriolide, a 12-membered macrolide from Chloridium virescens var. chlamydosporum (NRRL 37636)
- Creators
- PING Jiao - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesDale C Swenson - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesJames B Gloer - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesDonald T Wicklow - Mycotoxin Research Unit, Agricultural Research Service, National Center for Agricultural Utilization Research, USDA, Peoria, Illinois 61604, United States
- Resource Type
- Journal article
- Publication Details
- Journal of natural products (Washington, D.C.), Vol.69(4), pp.636-639
- Publisher
- American Society of Pharmacognosy
- DOI
- 10.1021/np0504964
- PMID
- 16643041
- ISSN
- 0163-3864
- eISSN
- 1520-6025
- Language
- English
- Date published
- 2006
- Academic Unit
- Chemistry
- Record Identifier
- 9984216667602771
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