Journal article
Choice of radioisotope in stereotactic interstitial radiotherapy of small brain tumors
Applied neurophysiology, Vol.50(1-6), pp.295-301
1987
DOI: 10.1159/000100730
PMID: 3329867
Abstract
In stereotactic interstitial radiotherapy, small radioactive sources are placed within the brain tumor to deliver locally high radiation doses. The choice of the radioisotope depends upon the dose distribution around the isotope, energy of the emitted radiation, relative biological effectiveness, and finally, the cost and availability of the isotope. We have analyzed 198gold, 125iodine and 192iridium in terms of these four factors. Our results have shown that 125I is superior to the other two isotopes due to its soft X-rays and dosimetric as well as radiobiological properties. Unfortunately, it is the most expensive of these radioisotopes, and can be difficult to obtain in specific activities.
Details
- Title: Subtitle
- Choice of radioisotope in stereotactic interstitial radiotherapy of small brain tumors
- Creators
- S K Jani - Division of Radiation Oncology, University of Iowa Hospitals and Clincs, Iowa CityP W HitchonJ C VanGilderE C PenningtonD H Hussey
- Resource Type
- Journal article
- Publication Details
- Applied neurophysiology, Vol.50(1-6), pp.295-301
- DOI
- 10.1159/000100730
- PMID
- 3329867
- NLM abbreviation
- Appl Neurophysiol
- ISSN
- 0302-2773
- Publisher
- Switzerland
- Language
- English
- Date published
- 1987
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiation Oncology; Neurosurgery
- Record Identifier
- 9984047619802771
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