Journal article
Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research
Wound repair and regeneration, Vol.23(1), pp.1-13
01/2015
DOI: 10.1111/wrr.12245
PMID: 25486905
Abstract
The incidence of chronic wounds is increased among older adults, and the impact of chronic wounds on quality of life is particularly profound in this population. It is well established that wound healing slows with age. However, the basic biology underlying chronic wounds and the influence of age-associated changes on wound healing are poorly understood. Most studies have used
in vitro
approaches and various animal models, but observed changes translate poorly to human healing conditions. The impact of age and accompanying multi-morbidity on the effectiveness of existing and emerging treatment approaches for chronic wounds is also unknown, and older adults tend to be excluded from randomized clinical trials. Poorly defined outcomes and variables, lack of standardization in data collection, and variations in the definition, measurement, and treatment of wounds also hamper clinical studies. The Association of Specialty Professors, in conjunction with the National Institute on Aging and the Wound Healing Society, held a workshop, summarized in this paper, to explore the current state of knowledge and research challenges, engage investigators across disciplines, and identify key research questions to guide future study of age-associated changes in chronic wound healing.
Details
- Title: Subtitle
- Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research
- Creators
- Lisa Gould - Wound Recovery and Hyperbaric Medicine Center, Kent HospitalPeter Abadir - Division of Geriatrics and Gerontology Medicine, Johns Hopkins UniversityHarold Brem - Department of Wound Healing and Regenerative Medicine, Winthrop University Hospital and School of Medicine, Stony Brook UniversityMarissa Carter - Strategic Solutions, IncTeresa Conner-Kerr - Department of Physical Therapy, Winston-Salem State UniversityJeff Davidson - Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of MedicineLuisa DiPietro - Center for Wound Healing and Tissue Regeneration, University of Illinois at ChicagoVincent Falanga - Department of Dermatology, Boston University School of MedicineCaroline Fife - Baylor College of Medicine, Department of Geriatrics, Houston, Texas and the St. Luke’s Wound Center, The WoodlandsSue Gardner - College of Nursing, University of IowaElizabeth Grice - Penn Institute for Immunology, University of PennsylvaniaJohn Harmon - Department of Surgery, Johns Hopkins UniversityWilliam R Hazzard - Gerontology and Geriatric Medicine, Wake Forest School of MedicineKevin P High - Department of Internal Medicine and Section on Infectious Diseases, Wake Forest School of MedicinePamela Houghton - School of Physical Therapy, Western UniversityNasreen Jacobson - Smith & NephewRobert S Kirsner - Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of MiamiElizabeth J Kovacs - Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University, ChicagoDavid Margolish - Department of Dermatology, University of PennsylvaniaFrances McFarland Horne - Association of Specialty ProfessorsMay J Reed - Division of Gerontology and Geriatric Medicine, University of WashingtonDennis H Sullivan - Department of Geriatrics, University of Arkansas for the Medical SciencesStephen Thom - Department of Emergency Medicine, University of MarylandMarjana Tomic-Canic - Wound Healing and Regenerative Medicine Research Program, Miller School of Medicine, University of MiamiJeremy Walston - Bloomberg School of Public Health, Johns Hopkins UniversityJoAnne Whitney - School of Nursing, University of WashingtonJohn Williams - National Institute on AgingSusan Zieman - National Institute on AgingKenneth Schmader - Durham VAMC and Duke University Medical Center
- Resource Type
- Journal article
- Publication Details
- Wound repair and regeneration, Vol.23(1), pp.1-13
- DOI
- 10.1111/wrr.12245
- PMID
- 25486905
- NLM abbreviation
- Wound Repair Regen
- ISSN
- 1067-1927
- eISSN
- 1524-475X
- Grant note
- DOI: 10.13039/100000909, name: John A. Hartford Foundation; DOI: 10.13039/100000049, name: National Institute on Aging
- Language
- English
- Date published
- 01/2015
- Academic Unit
- Nursing
- Record Identifier
- 9984063101702771
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