Journal article
Chronic obstructive pulmonary disease (COPD) and COPD-like phenotypes
Frontiers in medicine, Vol.11, 1375457
04/01/2024
DOI: 10.3389/fmed.2024.1375457
PMCID: PMC11037247
PMID: 38654838
Abstract
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease. Historically, two COPD phenotypes have been described: chronic bronchitis and emphysema. Although these phenotypes may provide additional characterization of the pathophysiology of the disease, they are not extensive enough to reflect the heterogeneity of COPD and do not provide granular categorization that indicates specific treatment, perhaps with the exception of adding inhaled glucocorticoids (ICS) in patients with chronic bronchitis. In this review, we describe COPD phenotypes that provide prognostication and/or indicate specific treatment. We also describe COPD-like phenotypes that do not necessarily meet the current diagnostic criteria for COPD but provide additional prognostication and may be the targets for future clinical trials.
Details
- Title: Subtitle
- Chronic obstructive pulmonary disease (COPD) and COPD-like phenotypes
- Creators
- Spyridon Fortis - University of IowaDimitris Georgopoulos - University of CreteNikolaos Tzanakis - University of CreteFrank Sciurba - University of PittsburghJoseph Zabner - University of IowaAlejandro P. Comellas - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Frontiers in medicine, Vol.11, 1375457
- Publisher
- Frontiers Media S.A
- DOI
- 10.3389/fmed.2024.1375457
- PMID
- 38654838
- PMCID
- PMC11037247
- ISSN
- 2296-858X
- Language
- English
- Date published
- 04/01/2024
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; ICTS; Internal Medicine
- Record Identifier
- 9984586459702771
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