Journal article
Cissampentin: A new bisbenzylisoquinoline alkaloid from Cissampelos fasciculata
Tetrahedron, Vol.49(7), pp.1337-1342
1993
DOI: 10.1016/S0040-4020(01)90186-3
Abstract
A new bisbenzylisoquinoline alkaloid, cissampentin, has been isolated from the aerial parts of Cissampelos fasciculata. Detailed interpretation of various spectra allowed identification of most structural features, including a rare methyleneoxy bridge. Although attempted methylation of this alkaloid led to complex mixtures, reaction with diethyl phosphorochloridate gave a single diethyl phosphate derivative and allowed assignment of a 7′-11 ether linkage. Bioassays indicate significant activity as a repellent to the leafcutter and Acromyrmex octospinosus, and limited antifungal activity. A new bisbenzylisoquinoline alkaloid, containing a rare methyleneoxy bridge, has been isolated from the aerial parts of Cissampelos fasciculata. Preparation of the diethyl phosphate derivative allowed assignment of the 7′-11 ether linkage. Bioassays indicate significant activity as a repellent to the leafcutter ant Acromyrmex octospinosus, and limited antifungal activity.
Details
- Title: Subtitle
- Cissampentin: A new bisbenzylisoquinoline alkaloid from Cissampelos fasciculata
- Creators
- Deborah L Galinis - Department of Chemistry University of Iowa Iowa City, Iowa 52242 U.S.ADavid F Wiemer - Department of Chemistry University of Iowa Iowa City, Iowa 52242 U.S.AJohn Cazin - Department of Microbiology University of Iowa Iowa City, Iowa 52242 U.S.A
- Resource Type
- Journal article
- Publication Details
- Tetrahedron, Vol.49(7), pp.1337-1342
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/S0040-4020(01)90186-3
- ISSN
- 0040-4020
- eISSN
- 1464-5416
- Language
- English
- Date published
- 1993
- Academic Unit
- Chemistry; Neuroscience and Pharmacology
- Record Identifier
- 9983985819502771
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