Journal article
Clearance of severely elevated plasma free hemoglobin with total plasma exchange in a pediatric ECMO patient
Perfusion, Vol.37(5), pp.515-518
07/2022
DOI: 10.1177/02676591211021946
PMID: 34058891
Abstract
Extracorporeal membrane oxygenation (ECMO)-related hemolysis is common with reported incidence of 5%–18%. Plasma free hemoglobin (PFH) levels are used as a marker for hemolysis and elevated PFH is associated with acute kidney injury (AKI). Limited literature exists regarding treatment of severe hemolysis and clearance of PFH. We report 8-year-old male child on VA ECMO with severe hemolysis (PFH 895 mg/dL) and worsening AKI showing significant improvement in PFH after single volume exchange plasmapheresis with Fresh Frozen Plasma (FFP) performed in tandem via ECMO circuit.
Details
- Title: Subtitle
- Clearance of severely elevated plasma free hemoglobin with total plasma exchange in a pediatric ECMO patient
- Creators
- Stephaine Houston - University of Iowa, Stead Family Department of PediatricsShruti Patel - University of IowaAditya Badheka - University of IowaKathy Lee-Son - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Perfusion, Vol.37(5), pp.515-518
- DOI
- 10.1177/02676591211021946
- PMID
- 34058891
- ISSN
- 0267-6591
- eISSN
- 1477-111X
- Language
- English
- Date published
- 07/2022
- Academic Unit
- Critical Care; Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics
- Record Identifier
- 9984354009502771
Metrics
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