Click modification of silica surfaces and glass microfluidic channels

Shaurya PRAKASH; Timothy M LONG; John C SELBY; Jeffrey S MOORE; Mark A SHANNON

doi:10.1021/ac061824n

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Click modification of silica surfaces and glass microfluidic channels

Journal article

Peer reviewed

Click modification of silica surfaces and glass microfluidic channels

Shaurya PRAKASH, Timothy M LONG, John C SELBY, Jeffrey S MOORE and Mark A SHANNON

Analytical chemistry (Washington), Vol.79(4), pp.1661-1667

2007

DOI: 10.1021/ac061824n

PMID: 17297970

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Abstract

This paper demonstrates a chemical surface modification method for covalent attachment of various polymers by using silane-based "click" chemistry on silica surfaces and within glass microchannels suitable for CE systems. Modified surfaces are characterized by contact angle measurements, X-ray photoelectron spectroscopy, and Fourier transform infrared-attenuated total reflection spectroscopy. Electroosmotic flow (EOF) measurements in modified and unmodified channels are provided. Spectroscopic and transport data show that various polymers can be covalently attached to glass surfaces with a measurable change in EOF.

Analytical Chemistry

Chemistry

Exact sciences and technology

Spectrometric and optical methods

Details

Title: Subtitle: Click modification of silica surfaces and glass microfluidic channels
Creators: Shaurya PRAKASH - Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
Timothy M LONG - Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
John C SELBY - Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
Jeffrey S MOORE - Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
Mark A SHANNON - Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
Resource Type: Journal article
Publication Details: Analytical chemistry (Washington), Vol.79(4), pp.1661-1667
Publisher: American Chemical Society; Washington, DC
DOI: 10.1021/ac061824n
PMID: 17297970
ISSN: 0003-2700
eISSN: 1520-6882
Language: English
Date published: 2007
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Dermatology
Record Identifier: 9984025442302771

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