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Climate variation drives dengue dynamics
Journal article   Open access   Peer reviewed

Climate variation drives dengue dynamics

Lei Xu, Leif C Stige, Kung-Sik Chan, Jie Zhou, Jun Yang, Shaowei Sang, Ming Wang, Zhicong Yang, Ziqiang Yan, Tong Jiang, …
Proceedings of the National Academy of Sciences - PNAS, Vol.114(1), pp.113-118
01/03/2017
DOI: 10.1073/pnas.1618558114
PMCID: PMC5224358
PMID: 27940911
url
https://doi.org/10.1073/pnas.1618558114View
Published (Version of record) Open Access

Abstract

Dengue, a viral infection transmitted between people by mosquitoes, is one of the most rapidly spreading diseases in the world. Here, we report the analyses covering 11 y (2005-2015) from the city of Guangzhou in southern China. Using the first 8 y of data to develop an ecologically based model for the dengue system, we reliably predict the following 3 y of dengue dynamics-years with exceptionally extensive dengue outbreaks. We demonstrate that climate conditions, through the effects of rainfall and temperature on mosquito abundance and dengue transmission rate, play key roles in explaining the temporal dynamics of dengue incidence in the human population. Our study thus contributes to a better understanding of dengue dynamics and provides a predictive tool for preventive dengue reduction strategies.
Aedes - virology Animals China - epidemiology Climate Climate Change Dengue - epidemiology Dengue - transmission Dengue Virus - pathogenicity Disease Outbreaks Humans Insect Vectors - virology Models, Theoretical Rain Temperature

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