Journal article
Clinical Characteristics, Outcomes, and Complications Associated With Delayed Diagnosis of Intraocular Foreign Body
Journal of vitreoretinal diseases (Print), Vol.9(4), pp.459-466
07/2025
DOI: 10.1177/24741264251339090
PMCID: PMC12122470
PMID: 40453423
Abstract
To describe the clinical characteristics, outcomes, and complications in cases of intraocular foreign bodies (IOFBs) when the diagnosis is missed or delayed.
This nonconsecutive case series was a retrospective multicenter study of adult patients with a delayed diagnosis of IOFB, defined as initially presenting elsewhere with a missed diagnosis or a delay of more than 24 hours to seek care.
Eighteen eyes were included. The mean (±SD) presenting logMAR visual acuity (VA) was 0.45 ± 0.70 (Snellen equivalent, 20/56). The most common presenting symptom was decreased vision (11 patients [61%]). The general emergency department setting accounted for most initial evaluations (11 patients [61%]); however, 6 patients (33%) were seen in an outpatient setting by an optometrist, ophthalmologist, or both. The most common anatomic locations of the IOFBs were in the iris/anterior chamber (4 [22%]) or lens (4 [22%]) followed by the pars plana/ciliary body (3 [17%]), vitreous (3 [17%]), or retina (3 [17%]). Complications at presentation included endophthalmitis (1 [6%]), retinal detachment (1 [6%]), and retinal tears (4 [22%]). Five patients (28%) had siderosis at presentation. The mean final logMAR VA was 0.13 ± 0.32 (Snellen equivalent, 20/26). At the last follow-up, 15 eyes (83%) had a VA of 20/30 or better. The median follow-up was 139 days (IQR, 86-557).
Eyes with a delayed diagnosis of IOFBs often present with good vision and self-sealing wounds. Missed IOFBs can be associated with siderosis, RD, and endophthalmitis. Visual outcomes may be salvaged with prompt treatment.
Details
- Title: Subtitle
- Clinical Characteristics, Outcomes, and Complications Associated With Delayed Diagnosis of Intraocular Foreign Body
- Creators
- Melissa Yuan - Massachusetts Eye and Ear InfirmaryLindsay K Kozek - Harvard Medical SchoolSandra Hoyek - Massachusetts Eye and Ear InfirmaryJose Davila - Massachusetts Eye and Ear InfirmaryLeo Kim - Massachusetts Eye and Ear InfirmaryFilippos Vingopoulos - Massachusetts Eye and Ear InfirmaryDan Gong - Massachusetts Eye and Ear InfirmaryLucy Young - Massachusetts Eye and Ear InfirmaryFrances Wu - Massachusetts Eye and Ear InfirmaryGrayson Armstrong - Harvard UniversityDean Eliott - Harvard UniversityMark P Breazzano - SUNY Upstate Medical UniversityRajeev Seth - Retina Vitreous Associates of FloridaJonathan F Russell - University of IowaJesse Sengillo - University of MiamiBenjamin Lin - University of MiamiBenjamin Fowler - Maine Medical CenterLucia Sobrin - Massachusetts Eye and Ear InfirmaryJohn B Miller - Harvard UniversityNimesh A Patel - Massachusetts Eye and Ear Infirmary
- Resource Type
- Journal article
- Publication Details
- Journal of vitreoretinal diseases (Print), Vol.9(4), pp.459-466
- DOI
- 10.1177/24741264251339090
- PMID
- 40453423
- PMCID
- PMC12122470
- NLM abbreviation
- J Vitreoretin Dis
- ISSN
- 2474-1264
- eISSN
- 2474-1272
- Publisher
- Sage
- Grant note
- VitreoRetinal Surgery FoundationRetina Innovation Fund, Massachusetts Eye and Ear, Boston, MA, USA
Dr. Hoyek is supported by the VitreoRetinal Surgery Foundation. Dr. Patel is supported by the Retina Innovation Fund, Massachusetts Eye and Ear, Boston, MA, USA. The Funding organizations had no role in the design or conduct of this research.
- Language
- English
- Electronic publication date
- 05/29/2025
- Date published
- 07/2025
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984827329302771
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