Clinical Efficacy of Biomimetic Bioactive Biomaterials for Dental Pulp Capping: A Systematic Review and Meta-Analysis

Liliana Argueta-Figueroa; Carlos Alberto Jurado; Rafael Torres-Rosas; Mario Alberto Bautista-Hernández; Abdulaziz Alhotan; Hamid Nurrohman

doi:10.3390/biomimetics7040211

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Clinical Efficacy of Biomimetic Bioactive Biomaterials for Dental Pulp Capping: A Systematic Review and Meta-Analysis

Journal article

Open access

Peer reviewed

Clinical Efficacy of Biomimetic Bioactive Biomaterials for Dental Pulp Capping: A Systematic Review and Meta-Analysis

Liliana Argueta-Figueroa, Carlos Alberto Jurado, Rafael Torres-Rosas, Mario Alberto Bautista-Hernández, Abdulaziz Alhotan and Hamid Nurrohman

Biomimetics (Basel, Switzerland), Vol.7(4), p.211

11/22/2022

DOI: 10.3390/biomimetics7040211

PMCID: PMC9775437

PMID: 36546911

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Abstract

Recently, biomimetic bioactive biomaterials have been introduced to the market for dental pulp capping. This systematic review and meta-analysis aimed to determine any variation between the effect of using TheraCal LC and other bioactive biomaterials for pulp capping is different, as measured by dentin increment and clinical success. The risk of bias was assessed using the Risk of Bias 2 and Newcastle-Ottawa tools for randomized clinical trials and observational studies. A search for relevant articles was performed on five databases. Additionally, the quality of the included studies was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. A summary of individual studies and a meta-analysis were performed. The odds ratio of data from clinical success was combined using a random-effects meta-analysis. The meta-analysis results showed homogeneity between the studies (I = 0%). They revealed that the clinical success showed no differences between the patients who received TheraCal LC, light-cured calcium silicate-based biomimetic biomaterial, for dental pulp capping or the comparator biomaterials ( > 0.5). However, the certainty of the evidence was low to moderate due to the risk of bias in the included studies.

permanent teeth

dentin increment

TheraCal LC

resin-modified pulp capping biomaterials

primary teeth

clinical success

pulp exposure

Details

Title: Subtitle: Clinical Efficacy of Biomimetic Bioactive Biomaterials for Dental Pulp Capping: A Systematic Review and Meta-Analysis
Creators: Liliana Argueta-Figueroa - Instituto Tecnológico de Toluca
Carlos Alberto Jurado - School of Dental Medicine, Texas Tech University Health Sciences Center, Woody L. Hunt School of Dental Medicine, 123 Rick Francis St, El Paso, TX 79905, USA
Rafael Torres-Rosas - Benito Juárez Autonomous University of Oaxaca
Mario Alberto Bautista-Hernández - Benito Juárez Autonomous University of Oaxaca
Abdulaziz Alhotan - King Saud University
Hamid Nurrohman - A.T. Still University
Resource Type: Journal article
Publication Details: Biomimetics (Basel, Switzerland), Vol.7(4), p.211
DOI: 10.3390/biomimetics7040211
PMID: 36546911
PMCID: PMC9775437
NLM abbreviation: Biomimetics (Basel)
ISSN: 2313-7673
eISSN: 2313-7673
Language: English
Date published: 11/22/2022
Academic Unit: Prosthodontics
Record Identifier: 9984367746302771

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