Clinical Evidence for Polyol Efficacy

P. Milgrom; E.M. Söderling; S. Nelson; D.L. Chi; Y. Nakai

doi:10.1177/0022034512449467

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Journal article

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Clinical Evidence for Polyol Efficacy

P. Milgrom, E.M. Söderling, S. Nelson, D.L. Chi and Y. Nakai

Advances in dental research, Vol.24(2), pp.112-116

09/01/2012

DOI: 10.1177/0022034512449467

PMCID: PMC3420363

PMID: 22899692

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https://europepmc.org/articles/pmc3420363View

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Abstract

Xylitol is a safe dental caries preventive when incorporated into chewing gum or confections used habitually. The goal of this paper is to identify and assess the work on xylitol and other polyols and dental caries since 2008. Xylitol is effective when used by the mother prenatally or after delivery to prevent mutans transmission and subsequent dental caries in the offspring. One new completed trial confirmed that children of mothers who used xylitol lozenges after delivery had less dental caries than a comparison group. A similar study confirmed that the use of xylitol gum by the mother either prevented or postponed MS transmission to the offspring. Xylitol use among schoolchildren delivered via a gummy bear confection reduced S. mutans levels, but a once per day use of xylitol-containing toothpaste did not. Randomized trials, with caries outcomes, assessing xylitol-containing lozenges in adults and xylitol-containing gummy bears in children will release results in the coming year. Other studies are ongoing but are not systematic and will fail to answer important questions about how xylitol, or other polyols, can address the global dental caries problem.

chewing gum

dental caries

erythritol

maltitol

prevention

xylitol

Details

Title: Subtitle: Clinical Evidence for Polyol Efficacy
Creators: P. Milgrom - University of Washington
E.M. Söderling - Turku University of Applied Sciences
S. Nelson - Case Western Reserve University
D.L. Chi - University of Washington
Y. Nakai - Okayama Shoka University
Resource Type: Journal article
Publication Details: Advances in dental research, Vol.24(2), pp.112-116
Publisher: SAGE Publications
DOI: 10.1177/0022034512449467
PMID: 22899692
PMCID: PMC3420363
ISSN: 0895-9374
eISSN: 1544-0737
Language: English
Date published: 09/01/2012
Academic Unit: Public Policy Center (Archive)
Record Identifier: 9984283850402771

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