Journal article
Clinical Importance of the Adrenergic Receptors
Archives of internal medicine (1960), Vol.118(5), pp.418-421
11/01/1966
DOI: 10.1001/archinte.1966.00290170006002
PMID: 5332027
Abstract
THE CONCEPT that cellular receptor mechanisms mediate the actions of drugs has been accepted for many years. Although the physicochemical and morphological properties of receptors in general are still poorly understood, a very active interest in the adrenergic receptors which subserve the actions of sympathomimetic amines has developed within the last decade. The increasing number of reports dealing with adrenergic receptors demonstrates that not only physiologists and pharmacologists but also internists and clinical investigators are preoccupied with this timely subject. A main reason for this sudden popularity is the recent discovery of compounds which block selectively certain cardiovascular and metabolic effects of the sympathomimetic amines leaving other effects of the amines unmodified. To the basic scientist the new blockers meant a better understanding of the mechanisms of action of adrenergic stimuli, and to the clinician they facilitated a clearer view of the pathophysiology of certain cardiovascular problems and permitted
Details
- Title: Subtitle
- Clinical Importance of the Adrenergic Receptors
- Creators
- FRANCOIS M ABBOUD
- Resource Type
- Journal article
- Publication Details
- Archives of internal medicine (1960), Vol.118(5), pp.418-421
- DOI
- 10.1001/archinte.1966.00290170006002
- PMID
- 5332027
- NLM abbreviation
- Arch Intern Med
- ISSN
- 0003-9926
- eISSN
- 1538-3679
- Publisher
- American Medical Association
- Language
- English
- Date published
- 11/01/1966
- Academic Unit
- Molecular Physiology and Biophysics; Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
- Record Identifier
- 9984025400602771
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