Journal article
Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study
Cardiovascular and interventional radiology, Vol.36(4), pp.978-986
08/01/2013
DOI: 10.1007/s00270-013-0611-5
PMID: 23580116
Abstract
Purpose
This study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH).
Methods
A prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year.
Results
Clinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12–41 months). At the first year follow-up, the mean IPSS score was 2.8 points (
p
= 0.04), mean QoL was 0.4 points (
p
= 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (
p
= 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (
p
= 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H
2
O (
p
= 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE.
Conclusions
Clinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies.
Details
- Title: Subtitle
- Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study
- Creators
- Alberto A. Antunes - Universidade de São PauloFrancisco C. Carnevale - Universidade de São PauloJoaquim M. da Motta Leal Filho - Universidade de São PauloEduardo M. Yoshinaga - Universidade de São PauloLuciana M. O. Cerri - Universidade de São PauloRonaldo H. Baroni - Universidade de São PauloAntonio S. Z. Marcelino - Universidade de São PauloGiovanni G. Cerri - Universidade de São PauloMiguel Srougi - Universidade de São Paulo
- Resource Type
- Journal article
- Publication Details
- Cardiovascular and interventional radiology, Vol.36(4), pp.978-986
- DOI
- 10.1007/s00270-013-0611-5
- PMID
- 23580116
- NLM abbreviation
- Cardiovasc Intervent Radiol
- ISSN
- 0174-1551
- eISSN
- 1432-086X
- Publisher
- Springer New York
- Language
- English
- Date published
- 08/01/2013
- Academic Unit
- Radiology
- Record Identifier
- 9984697619202771
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