Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

Alberto A. Antunes; Francisco C. Carnevale; Joaquim M. da Motta Leal Filho; Eduardo M. Yoshinaga; Luciana M. O. Cerri; Ronaldo H. Baroni; Antonio S. Z. Marcelino; Giovanni G. Cerri; Miguel Srougi

doi:10.1007/s00270-013-0611-5

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Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

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Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

Alberto A. Antunes, Francisco C. Carnevale, Joaquim M. da Motta Leal Filho, Eduardo M. Yoshinaga, Luciana M. O. Cerri, Ronaldo H. Baroni, Antonio S. Z. Marcelino, Giovanni G. Cerri and Miguel Srougi

Cardiovascular and interventional radiology, Vol.36(4), pp.978-986

08/01/2013

DOI: 10.1007/s00270-013-0611-5

PMID: 23580116

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Abstract

Purpose This study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH). Methods A prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year. Results Clinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12–41 months). At the first year follow-up, the mean IPSS score was 2.8 points (p = 0.04), mean QoL was 0.4 points (p = 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (p = 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (p = 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H2O (p = 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE. Conclusions Clinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies.

Cardiology

Nuclear Medicine

Radiology

Clinical Investigation

Imaging

Medicine

Medicine & Public Health

Ultrasound

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Title: Subtitle: Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study
Creators: Alberto A. Antunes - Universidade de São Paulo
Francisco C. Carnevale - Universidade de São Paulo
Joaquim M. da Motta Leal Filho - Universidade de São Paulo
Eduardo M. Yoshinaga - Universidade de São Paulo
Luciana M. O. Cerri - Universidade de São Paulo
Ronaldo H. Baroni - Universidade de São Paulo
Antonio S. Z. Marcelino - Universidade de São Paulo
Giovanni G. Cerri - Universidade de São Paulo
Miguel Srougi - Universidade de São Paulo
Resource Type: Journal article
Publication Details: Cardiovascular and interventional radiology, Vol.36(4), pp.978-986
DOI: 10.1007/s00270-013-0611-5
PMID: 23580116
NLM abbreviation: Cardiovasc Intervent Radiol
ISSN: 0174-1551
eISSN: 1432-086X
Publisher: Springer New York
Language: English
Date published: 08/01/2013
Academic Unit: Radiology
Record Identifier: 9984697619202771

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