Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan

Shin-ichiro Hagiwara; Takahiro Kudo; Fumihiko Kakuta; Mikihiro Inoue; Koji Yokoyama; Shuichiro Umetsu; Itaru Iwama; Toshifumi Yodoshi; Maiko Tatsuki; Toshiaki Shimizu; Yoshiko Nakayama

doi:10.1097/MPG.0000000000002181

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Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan

Journal article

Peer reviewed

Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan

Shin-ichiro Hagiwara, Takahiro Kudo, Fumihiko Kakuta, Mikihiro Inoue, Koji Yokoyama, Shuichiro Umetsu, Itaru Iwama, Toshifumi Yodoshi, Maiko Tatsuki, Toshiaki Shimizu, …

Journal of pediatric gastroenterology and nutrition, Vol.68(3), pp.306-310

03/2019

DOI: 10.1097/MPG.0000000000002181

PMID: 30444835

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Abstract

Objectives: The benefit of balloon-assisted enteroscopy (BAE) had been recently documented in pediatric patients, but previous reports are based on single institution experiences. We evaluated the feasibility of pediatric BAE in 8 tertiary referral hospitals throughout Japan. Methods: This was a prospective, multi-institutional study. Patients younger than 18 years were enrolled between April 2014 and March 2017 to undergo double-balloon or single-balloon enteroscopy. Data were collected prospectively using a standardized questionnaire. Results: We enrolled 79 pediatric patients (96 procedures, 70 boys, 26 girls; median age 12.7 years, range 1-17 years). Antegrade (oral-route) BAE was performed in 20 procedures (lowest body weight 12.9 kg, youngest age 3.7 years), and retrograde (anal-route) BAE in 76 (lowest body weight 10.8 kg, youngest age 1.6 years). Severe adverse events were associated with BAE in 2 patients: 1 with hemorrhage due to polypectomy and 1 with pancreatitis after double-balloon endoscopic retrograde cholangioscopy. No intestinal perforation was reported. Procedure duration of oral-route BAE for diagnosis was significantly longer than anal-route for diagnosis (P<0.001). The overall diagnostic yield for rectal bleeding/positive fecal occult blood test and abdominal pain was 48%. Among 40 patients referred for diagnosis who did not undergo capsule endoscopy, diagnoses were confirmed in 17 (42.5%) patients after BAE. Conclusions: This prospective multicenter observational study documents the efficacy of BAE in pediatric patients.

Pediatrics

Gastroenterology & Hepatology

Life Sciences & Biomedicine

Nutrition & Dietetics

Science & Technology

Details

Title: Subtitle: Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan
Creators: Shin-ichiro Hagiwara - Saitama Children's Medical Center
Takahiro Kudo - Juntendo University
Fumihiko Kakuta - Miyagi Children's Hospital
Mikihiro Inoue - Mie University
Koji Yokoyama - Jichi Medical University
Shuichiro Umetsu - Saiseikai Kanagawa Hospital
Itaru Iwama - Saitama Children's Medical Center
Toshifumi Yodoshi - Okinawa Prefectural Chubu Hospital
Maiko Tatsuki - Gunma University
Toshiaki Shimizu - Juntendo University
Yoshiko Nakayama - Shinshu University
Resource Type: Journal article
Publication Details: Journal of pediatric gastroenterology and nutrition, Vol.68(3), pp.306-310
DOI: 10.1097/MPG.0000000000002181
PMID: 30444835
NLM abbreviation: J Pediatr Gastroenterol Nutr
ISSN: 0277-2116
eISSN: 1536-4801
Publisher: Wiley
Number of pages: 5
Language: English
Date published: 03/2019
Academic Unit: Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition
Record Identifier: 9985214100402771

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