Journal article
Clinical and Bacteriologic Observations of a Toxic Shock–like Syndrome Due to Streptococcus pyogenes
The New England journal of medicine, Vol.317(3), pp.146-149
07/16/1987
DOI: 10.1056/NEJM198707163170305
PMID: 3299086
Abstract
IN 1978, Todd et al.
1
described a multisystem clinical syndrome (toxic shock syndrome) characterized by the sudden onset of fever, rash, vomiting and diarrhea, hypotension, conjunctival injection, and strawberry tongue, followed by desquamation during recovery. The syndrome has been associated with colonization or infection by a toxin-producing
Staphylococcus aureus
. A toxin with a molecular weight of 22,049, toxic shock syndrome toxin-1, formerly termed staphylococcal enterotoxin F or pyrogenic exotoxin C, has been identified as the staphylococcal product responsible for the disorder.
2
3
4
5
All three toxins are chemically and immunologically identical. Recently, staphylococcal enterotoxin B has been associated with nonmenstrual toxic . . .
Details
- Title: Subtitle
- Clinical and Bacteriologic Observations of a Toxic Shock–like Syndrome Due to Streptococcus pyogenes
- Creators
- Lawrence A ConeDavid R WoodardPatrick M SchlievertGerald S Tomory
- Resource Type
- Journal article
- Publication Details
- The New England journal of medicine, Vol.317(3), pp.146-149
- Publisher
- Massachusetts Medical Society
- DOI
- 10.1056/NEJM198707163170305
- PMID
- 3299086
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Language
- English
- Date published
- 07/16/1987
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984001136102771
Metrics
56 Record Views