Clinical and financial impact of obesity on the outcome of liver transplantation

T Fujikawa; S Fujita; S Mizuno; E Shenkman; B Vogel; P Lipori; A W Hemming; D Nelson; A I Reed

doi:10.1016/j.transproceed.2006.10.188

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Clinical and financial impact of obesity on the outcome of liver transplantation

Journal article

Peer reviewed

Clinical and financial impact of obesity on the outcome of liver transplantation

T Fujikawa, S Fujita, S Mizuno, E Shenkman, B Vogel, P Lipori, A W Hemming, D Nelson and A I Reed

Transplantation proceedings, Vol.38(10), pp.3612-3614

12/2006

DOI: 10.1016/j.transproceed.2006.10.188

PMID: 17175347

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Abstract

The purpose of this study was to determine whether body mass index (BMI) influences the clinical outcomes and overall cost of transplantation in adult liver transplantation (OLT) using records of 700 adult OLT recipients. Patients were divided into BMI range groups over the range of 15 to 42 (mean = 26.7), namely: <25, n = 288 (41%); 25 to 30, n = 245 (35%); > or =30, n = 167 (24%). Only a small subset of this last group was morbidly obese (BMI > or = 35, n = 37, 5% of total). We did not detect an effect of BMI on patient or graft survival, the incidence of acute graft rejection, or major surgical complications. BMI was not related to length of hospital stay. There were no statistical differences between the three groups with respect to the ratio of overall hospital cost in a general linear model, corrected for age, gender, calculated Model for End-Stage Liver Disease score, retransplant status, or return to the operating room. In conclusion, obesity did not influence either the costs or the clinical outcomes following OLT. Further analysis of the morbidly obese population with respect to cost and outcome is warranted.

Body Mass Index

Humans

Cost of Illness

Graft Survival

Liver Transplantation - mortality

Obesity - physiopathology

Treatment Outcome

Florida

Liver Transplantation - physiology

Regression Analysis

Liver Transplantation - economics

Obesity, Morbid - physiopathology

Survival Analysis

Adult

Retrospective Studies

Liver Failure - surgery

Obesity - economics

Cohort Studies

Details

Title: Subtitle: Clinical and financial impact of obesity on the outcome of liver transplantation
Creators: T Fujikawa - Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610-0286, USA. fujita@surgery.ufl.edu
S Fujita
S Mizuno
E Shenkman
B Vogel
P Lipori
A W Hemming
D Nelson
A I Reed
Resource Type: Journal article
Publication Details: Transplantation proceedings, Vol.38(10), pp.3612-3614
Publisher: United States
DOI: 10.1016/j.transproceed.2006.10.188
PMID: 17175347
ISSN: 0041-1345
eISSN: 1873-2623
Language: English
Date published: 12/2006
Academic Unit: Accounting; Surgery
Record Identifier: 9984051535902771

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