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Clinical and histologic comparison of two different composite grafts for sinus augmentation: a pilot clinical trial
Journal article   Peer reviewed

Clinical and histologic comparison of two different composite grafts for sinus augmentation: a pilot clinical trial

Pablo Galindo-Moreno, Gustavo Avila, Juan Emilio Fernández-Barbero, Francisco Mesa, Francisco O'Valle-Ravassa and Hom-Lay Wang
Clinical oral implants research, Vol.19(8), pp.755-759
08/2008
DOI: 10.1111/j.1600-0501.2008.01536.x
PMID: 18573123
url
https://hdl.handle.net/2027.42/73800View
Open Access

Abstract

Sinus augmentation is a procedure used for augmenting insufficient bone height that is often observed in the maxillary posterior areas. Many different techniques as well as bone graft regimens have been suggested for performing this procedure. It was the goal of this study to compare, clinically and histologically, two different composite grafting regimens used for sinus augmentation. Five patients, needing a bilateral sinus augmentation to allow implant placement, were recruited for this study. Right sinuses were grafted with cortical bone (collected from overlying the sinus membrane) and bovine hydroxyapatite (HA), while the left side sinuses were grafted with overlying autologous bone plus a bioglass (BG) material. Bone core biopsies were taken at 6 months after sinus graft or at the time of implant insertion. A waiting period of 6 additional months was granted to allow healing, before prosthetic restoration and functional loading. The level of peri-implant bone was evaluated 12 months after loading. A comparative histomorphometric analysis was conducted and a statistical analysis was performed. All implants in both groups were functional after a 12-month loading period. No bone loss was observed radiographically or clinically in both groups. Histologic analysis revealed that both composite grafts had a high biocompatibility. In the bovine HA-containing group, minimal xenogenic graft absorption was noted. In contrast, BG group samples presented a high absorption rate with some remaining particles imbedded in new normal bone. Sinus augmentation using a combination of autogenous bone plus either bovine HA or BG is a predictable technique.
 Humans Middle Aged Male Ceramics - therapeutic use Maxilla - surgery Minerals - therapeutic use Alveolar Bone Loss - surgery Bone Matrix - transplantation Cattle Oral Surgical Procedures, Preprosthetic - methods Maxillary Sinus - pathology Maxilla - pathology Alveolar Ridge Augmentation - methods Treatment Outcome Alveolar Bone Loss - pathology Maxillary Sinus - surgery Pilot Projects Animals Bone Substitutes - therapeutic use Aged Biocompatible Materials - therapeutic use Dental Implants Guided Tissue Regeneration, Periodontal - methods Dental Implantation, Endosseous - methods Bone Transplantation - methods Dental Restoration, Permanent - methods

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