Journal article
Clinical approach to neuro-rheumatology
Journal of the neurological sciences, Vol.431, pp.120048-120048
12/15/2021
DOI: 10.1016/j.jns.2021.120048
Abstract
Recognizing the neurologic manifestations of systemic rheumatologic diseases and certain isolated autoimmune neurologic diseases poses challenges to the clinician. Using a systematic approach allows the clinician to diagnose these conditions more readily and to initiate treatment more rapidly. Specific neurological syndromes frequently associated with rheumatologic or specific autoimmune conditions can suggest the diagnosis. A targeted history and examination can identify neurological and systemic clues that help to identify an underlying rheumatologic condition. Judicious use of laboratory and radiographic studies can help confirm suspected diagnoses. This article will review some of the neurological syndromes typical of rheumatologic disease and outline an approach to evaluating for unknown rheumatologic disease in this context.
•Rheumatologic causes of pachymeningitis include IgG4-related disease, neurosarcoidosis, and ANCA-associated vasculitis.•Sensory neuronopathy is most commonly seen in Sjogren syndrome or as a paraneoplastic syndrome with small cell lung cancer.•Mononeuritis multiplex should always prompt evaluation for systemic vasculitis.•Ocular inflammation may be seen in a number of rheumatologic.•Dermatologic manifestations of rheumatologic disease are diverse but can clue to the underlying diagnosis.
Details
- Title: Subtitle
- Clinical approach to neuro-rheumatology
- Creators
- Sarah GoglinTracey A Cho - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of the neurological sciences, Vol.431, pp.120048-120048
- Publisher
- Elsevier B.V
- DOI
- 10.1016/j.jns.2021.120048
- ISSN
- 0022-510X
- eISSN
- 1878-5883
- Language
- English
- Date published
- 12/15/2021
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984197395602771
Metrics
11 Record Views