Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid

Gene R Howard; Jeffrey A Nerad; Keith D Carter; Duane C Whitaker

doi:10.1016/s0002-9394(14)71523-5

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Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid

Journal article

Peer reviewed

Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid

Gene R Howard, Jeffrey A Nerad, Keith D Carter and Duane C Whitaker

American journal of ophthalmology, Vol.113(2), pp.123-133

02/15/1992

DOI: 10.1016/s0002-9394(14)71523-5

PMID: 1550179

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Abstract

Over a six-year period, between 1984 and 1990, 622 patients with basal cell and squamous cell carcinoma of the eyelids were examined at our institution. Thirteen patients had orbital invasion at initial examination. The average age of patients at orbital invasion was 75.8 years. Ten patients were men, eight of whom had basal cell carcinoma and two of whom had squamous cell carcinoma. Most patients had an orbital mass and incomitant strabismus at initial examination. Invasive basal cell carcinoma developed in 11 patients, and squamous cell carcinoma developed in two patients. Ten patients were treated for cutaneous carcinoma at the site of invasion before examination at our institution. The average duration between onset of a cutaneous lesion and our examination for orbital invasion was 9.8 years for basal cell carcinoma and one year for squamous cell carcinoma. Radiologic and histopathologic features were reviewed. The clinical characteristics of these patients were reviewed and orbital exenteration was recommended to all 13 patients. Nine patients underwent exenteration and four refused the operation.

Magnetic Resonance Imaging

Carcinoma, Basal Cell - radiotherapy

Eye Enucleation

Neoplasm Invasiveness

Carcinoma, Squamous Cell - pathology

Humans

Middle Aged

Orbital Neoplasms - pathology

Carcinoma, Squamous Cell - surgery

Male

Tomography, X-Ray Computed

Carcinoma, Basal Cell - pathology

Eyelid Neoplasms - pathology

Carcinoma, Squamous Cell - radiotherapy

Carcinoma, Basal Cell - surgery

Eyelid Neoplasms - surgery

Eyelid Neoplasms - radiotherapy

Aged, 80 and over

Female

Aged

Orbital Neoplasms - surgery

Orbital Neoplasms - radiotherapy

Details

Title: Subtitle: Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid
Creators: Gene R Howard - Oculoplastic and Orbital Surgery Service, University of Iowa Hospitals and Clinics, Iowa City 52242
Jeffrey A Nerad
Keith D Carter
Duane C Whitaker
Resource Type: Journal article
Publication Details: American journal of ophthalmology, Vol.113(2), pp.123-133
DOI: 10.1016/s0002-9394(14)71523-5
PMID: 1550179
NLM abbreviation: Am J Ophthalmol
ISSN: 0002-9394
eISSN: 1879-1891
Publisher: United States
Language: English
Date published: 02/15/1992
Academic Unit: Otolaryngology; Ophthalmology and Visual Sciences
Record Identifier: 9983980030402771

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