Journal article
Clinical correlates, outcomes and healthcare costs associated with early mechanical ventilation after kidney transplantation
The American journal of surgery, Vol.206(5), pp.686-692
11/2013
DOI: 10.1016/j.amjsurg.2013.07.008
PMID: 24157349
Abstract
Information is lacking on the frequency, clinical implications, and costs of respiratory failure requiring mechanical ventilation after kidney transplantation.
US Renal Data System records for Medicare-insured kidney transplant recipients (1995 to 2007; n = 88,392) were examined to identify post-transplantation mechanical ventilation from billing claims within 30 days after transplantation.
Post-transplantation mechanical ventilation was required among 2.1% of the cohort. Independent correlates of early mechanical ventilation included recipient age, low body mass index, coronary artery disease, and cerebrovascular disease. Post-transplantation mechanical ventilation was twice as likely with delayed graft function (adjusted odds ratio, 2.13; P < .001) and 35% lower among recipients of living versus deceased donor allografts. Patients needing early mechanical ventilation experienced 5-fold higher 1-year mortality, as well as significantly higher Medicare costs during the transplant hospitalization and first post-transplantation year.
Recognition of patients at risk for post-transplantation respiratory failure may help direct protocols for reducing the incidence and consequences of this complication.
Details
- Title: Subtitle
- Clinical correlates, outcomes and healthcare costs associated with early mechanical ventilation after kidney transplantation
- Creators
- Hui Yuan - Saint Louis UniversityJanet E. Tuttle-Newhall - Saint Louis UniversityMark Dy-Liacco - Saint Louis UniversityMark A. Schnitzler - Saint Louis UniversityNino Dzebisashvili - Dartmouth–Hitchcock Medical CenterHuiling Xiao - Saint Louis UniversityDavid Axelrod - Dartmouth–Hitchcock Medical CenterBrian Holt - Saint Louis UniversityKrista L. Lentine - Saint Louis University
- Resource Type
- Journal article
- Publication Details
- The American journal of surgery, Vol.206(5), pp.686-692
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.amjsurg.2013.07.008
- PMID
- 24157349
- ISSN
- 0002-9610
- eISSN
- 1879-1883
- Language
- English
- Date published
- 11/2013
- Academic Unit
- Surgery
- Record Identifier
- 9984322820202771
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