Journal article
Clinical, historic, and therapeutic features of cicatricial pemphigoid : a literature review and open therapeutic trial with corticosteroids
Oral surgery, oral medicine, oral pathology, Vol.76(4), pp.453-459
1993
DOI: 10.1016/0030-4220(93)90012-S
PMID: 8233425
Abstract
Cicatricial pemphigoid is at present an incurable, autoimmune disease that involves mucosa and skin. We have documented the clinical, microscopic, and therapeutic features of 23 patients with cicatricial pemphigoid and added these to reports of past literature. The mean age at the time of diagnosis was 63 years, and women were involved twice as often as men. Eighty-three percent of patients had oral mucosal involvement, 70% had conjunctival involvement, and 22% had skin involved. Direct immunologic evaluation revealed IgG at the basement membrane in 57% of cases and C3 in 66%. We have been able to manage the disease adequately in most patients with topical or systemic corticosteroids. The most commonly encountered side effect was oral candidiasis.
Details
- Title: Subtitle
- Clinical, historic, and therapeutic features of cicatricial pemphigoid : a literature review and open therapeutic trial with corticosteroids
- Creators
- S. D VINCENT - Univ. Iowa coll. dentistry, dep. oral pathology radiology medicine, Iowa City IA 52242, United StatesG. E LILLY - Univ. Iowa coll. dentistry, dep. oral pathology radiology medicine, Iowa City IA 52242, United StatesK. A BAKER - Univ. Iowa coll. dentistry, dep. oral pathology radiology medicine, Iowa City IA 52242, United States
- Resource Type
- Journal article
- Publication Details
- Oral surgery, oral medicine, oral pathology, Vol.76(4), pp.453-459
- Publisher
- Mosby; Saint Louis, MO
- DOI
- 10.1016/0030-4220(93)90012-S
- PMID
- 8233425
- ISSN
- 0030-4220
- eISSN
- 1878-2175
- Language
- English
- Date published
- 1993
- Academic Unit
- Oral Pathology, Radiology and Medicine; Pathology; Pharmacy Practice and Science
- Record Identifier
- 9984065699702771
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