Journal article
Clinical utility of diffusion-weighted magnetic resonance imaging in prostate cancer
BJU international, Vol.108(11), pp.1716-1722
12/2011
DOI: 10.1111/j.1464-410X.2011.10256.x
PMID: 21631696
Abstract
What's known on the subject? and What does the study add? This article reviews what is currently known about diffusion weighted MRI (DW-MRI) in prostate cancer. This mini-review concisely summarises, for clinical managing patients with prostate cancer, the clinical utility of diffusion weighted MRI.
• To review the clinical utility of diffusion-weighted magnetic resonance imaging (DW-MRI) in patients with prostate cancer.
• The current literature on prostate cancer and DW-MRI was reviewed.
• DW-MRI can be readily acquired on a modern scanner with a short image acquisition time and no need for i.v. contrast medium. • The image contrast is based on the diffusion of water molecules and thus reflects tissue cellularity. • There is increasing evidence that DW- MRI improves the sensitivity and specificity of prostate cancer detection as well as the identification of tumour aggressiveness. • DW-MRI is also showing substantial promise as a response biomarker for both local and metastatic disease
• DW-MRI is proving to be a useful adjunct to conventional T2-weighted MRI sequences. • The eventual role of DW-MRI in combination with other MRI techniques for multiparametric assessment of prostate cancer needs to be defined further.
Details
- Title: Subtitle
- Clinical utility of diffusion-weighted magnetic resonance imaging in prostate cancer
- Creators
- Asim Afaq - Royal Marsden HospitalDow-Mu Koh - Royal Marsden HospitalAnwar Padhani - Mount Vernon HospitalNicholas van As - Royal Marsden HospitalS Aslam Sohaib - Royal Marsden Hospital
- Resource Type
- Journal article
- Publication Details
- BJU international, Vol.108(11), pp.1716-1722
- DOI
- 10.1111/j.1464-410X.2011.10256.x
- PMID
- 21631696
- ISSN
- 1464-4096
- eISSN
- 1464-410X
- Language
- English
- Date published
- 12/2011
- Academic Unit
- Radiology
- Record Identifier
- 9984318719502771
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