Journal article
Clinical validation of a real-time applicator position monitoring system for gynecologic intracavitary brachytherapy
Biomedical physics & engineering express, Vol.2(4), p.45008
07/27/2016
DOI: 10.1088/2057-1976/2/4/045008
Abstract
Purpose: To validate the clinical feasibility and efficacy of a real-time applicator position monitoring system (RAPS) through a phantom study and a prospective clinical trial. Methods and materials: The RAPS measures the brachytherapy applicator displacement in real-time by computing the relative displacement between two infrared reflective targets, one attached to the applicator and the other to the patient's skin. A phantom study was performed to compare RAPS measurements with the ground truth. Six cervical cancer patients were enrolled in the clinical trial using MRI-based high-dose-rate brachytherapy with a Tandem-and-Ovoids applicator. The results from the RAPS are compared with the clinical method. Results: In the phantom study, an average difference between RAPS measurements and known displacements was 0.02 0.01 mm in the superior-inferior direction, 0.02 0.02 mm in the lateral direction, and 0.11 0.06 mm in the anterior-posterior direction. In the clinical trial, the absolute difference in applicator displacement between the RAPS and the clinical method was 1.46 1.13 mm. In all patient cases, a maximum applicator displacement of 6.66 mm (2.0 1.5 mm) was observed using the RAPS. Conclusions: This work demonstrates the clinical efficacy of RAPS to measure applicator displacement.
Details
- Title: Subtitle
- Clinical validation of a real-time applicator position monitoring system for gynecologic intracavitary brachytherapy
- Creators
- Wassim Bou-Zeid - University of IowaChristian Bauer - University of IowaYusung Kim - University of IowaReinhard R Beichel - University of IowaWenqing Sun - University of IowaTimothy Waldron - University of IowaJunyi Xia - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Biomedical physics & engineering express, Vol.2(4), p.45008
- Publisher
- IOP Publishing
- DOI
- 10.1088/2057-1976/2/4/045008
- ISSN
- 2057-1976
- eISSN
- 2057-1976
- Number of pages
- 8
- Grant note
- Varian Medical Systems (http://dx.doi.org/10.13039/100007210)
- Language
- English
- Date published
- 07/27/2016
- Academic Unit
- Electrical and Computer Engineering; Radiation Oncology
- Record Identifier
- 9984197456502771
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