Journal article
Clonal Immunoglobulin Gene Rearrangement in Nodular Lymphoid Hyperplasia of the Gastrointestinal Tract Associated with Common Variable Immunodeficiency
American journal of clinical pathology, Vol.94(3), pp.338-343
09/01/1990
DOI: 10.1093/ajcp/94.3.338
PMID: 2204266
Abstract
The authors report a case of common variable immunodeficiency associated with nodular lymphoid hyperplasia of the gastrointestinal tract in which a clonal population of lymphoid cells was detected by immunophenotypic and genotypic studies on tissue obtained by colonoscopic biopsy. The patient has been followed up for more than 50 months without clinical, radiographic, or pathologic evidence of lymphoma. The significance of clonal rearrangement in the setting of immunodeficiency and the role of genotypic studies in defining lymphoid malignancy are discussed.
Details
- Title: Subtitle
- Clonal Immunoglobulin Gene Rearrangement in Nodular Lymphoid Hyperplasia of the Gastrointestinal Tract Associated with Common Variable Immunodeficiency
- Creators
- Michael J Laszewski - University of Iowa Hospitals and ClinicsJohn D Kemp - University of Iowa Hospitals and ClinicsJames A Goeken - University of Iowa Hospitals and ClinicsFrank A Mitros - University of Iowa Hospitals and ClinicsCharles E Platz - University of Iowa Hospitals and ClinicsFred R Dick - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- American journal of clinical pathology, Vol.94(3), pp.338-343
- DOI
- 10.1093/ajcp/94.3.338
- PMID
- 2204266
- ISSN
- 0002-9173
- eISSN
- 1943-7722
- Language
- English
- Date published
- 09/01/1990
- Academic Unit
- Pathology
- Record Identifier
- 9984203945902771
Metrics
4 Record Views