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Cloning genes for non-syndromal hearing impairment
Journal article   Peer reviewed

Cloning genes for non-syndromal hearing impairment

R. J. H Smith and Guy Camp
British journal of audiology, Vol.33(5), pp.271-278
01/01/1999
DOI: 10.3109/03005369909090109
PMID: 10890140

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Abstract

Over 45 genes that cause autosomal non-syndromic hearing impairment (NSHI) have been localized and many more are predicted to exist. To clone these genes, a number of different strategies can be used. This paper focuses on four general approaches: functional cloning, positional cloning, position-dependent candidate gene cloning, and position-independent candidate gene cloning.

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