Journal article
Coagulopathy, Marantic Endocarditis, and Cerebrovascular Accidents as Paraneoplastic Features in Medullary Thyroid Cancer—Case Report and Review of the Literature
Thyroid (New York, N.Y.), Vol.13(6), pp.601-605
06/2003
DOI: 10.1089/105072503322238872
PMID: 12930605
Abstract
Medullary thyroid cancers account for approximately 7% of primary thyroid malignancies and are often associated with paraneoplastic syndromes. We discuss the case of a 59-year-old man who presented with a hypercoagulable state, nonbacterial endocarditis, and recurrent strokes in the setting of widespread medullary thyroid cancer. The patient was anticoagulated and underwent thyroidectomy, modified radical neck dissection, and subsequent axillary lymphadenectomy. Despite no recurrent thromboembolic events, the patient ultimately succumbed to his disease 8 months after diagnosis and 6 months after initial thyroidectomy. This is the first report, to our knowledge, of this unique presentation in a patient with thyroid cancer. The literature pertaining to the diagnosis and management of hypercoagulability states in patients with cancer, in general, and thyroid cancer, in particular, is reviewed.
Details
- Title: Subtitle
- Coagulopathy, Marantic Endocarditis, and Cerebrovascular Accidents as Paraneoplastic Features in Medullary Thyroid Cancer—Case Report and Review of the Literature
- Creators
- Geeta Lal - University of California San Francisco Medical CenterTodd V. Brennan - University of California, San FranciscoJulie Hambleton - University of California, San FranciscoOrlo H. Clark - University of California, San Francisco
- Resource Type
- Journal article
- Publication Details
- Thyroid (New York, N.Y.), Vol.13(6), pp.601-605
- DOI
- 10.1089/105072503322238872
- PMID
- 12930605
- ISSN
- 1050-7256
- eISSN
- 1557-9077
- Language
- English
- Date published
- 06/2003
- Academic Unit
- Stead Family Department of Pediatrics; Surgery
- Record Identifier
- 9984322828102771
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