Coding of Repetitive Transients by Auditory Cortex on Heschl's Gyrus

John F Brugge; Kirill V Nourski; Hiroyuki Oya; Richard A Reale; Hiroto Kawasaki; Mitchell Steinschneider; Matthew A Howard

doi:10.1152/jn.91346.2008

Back

Coding of Repetitive Transients by Auditory Cortex on Heschl's Gyrus

Journal article

Open access

Peer reviewed

Coding of Repetitive Transients by Auditory Cortex on Heschl's Gyrus

John F Brugge, Kirill V Nourski, Hiroyuki Oya, Richard A Reale, Hiroto Kawasaki, Mitchell Steinschneider and Matthew A Howard

Journal of neurophysiology, Vol.102(4), pp.2358-2374

10/2009

DOI: 10.1152/jn.91346.2008

PMCID: PMC2775384

PMID: 19675285

Files and links (1)

url

https://doi.org/10.1152/jn.91346.2008View

Published (Version of record) Open Access

Abstract

The capacity of auditory cortex on Heschl's gyrus (HG) to encode repetitive transients was studied in human patients undergoing surgical evaluation for medically intractable epilepsy. Multicontact depth electrodes were chronically implanted in gray matter of HG. Bilaterally presented stimuli were click trains varying in rate from 4 to 200 Hz. Averaged evoked potentials (AEPs) and event-related band power (ERBP), computed from responses at each of 14 recording sites, identified two auditory fields. A core field, which occupies posteromedial HG, was characterized by a robust polyphasic AEP on which could be superimposed a frequency following response (FFR). The FFR was prominent at click rates below ∼50 Hz, decreased rapidly as click rate was increased, but could reliably be detected at click rates as high as 200 Hz. These data are strikingly similar to those obtained by others in the monkey under essentially the same stimulus conditions, indicating that mechanisms underlying temporal processing in the auditory core may be highly conserved across primate species. ERBP, which reflects increases or decreases of both phase-locked and non–phase-locked power within given frequency bands, showed stimulus-related increases in gamma band frequencies as high as 250 Hz. The AEPs recorded in a belt field anterolateral to the core were typically of low amplitude, showing little or no evidence of short-latency waves or an FFR, even at the lowest click rates used. The non–phase-locked component of the response extracted from the ERBP showed a robust, long-latency response occurring here in response to the highest click rates in the series.

Details

Title: Subtitle: Coding of Repetitive Transients by Auditory Cortex on Heschl's Gyrus
Creators: John F Brugge - Department of Neurosurgery, University of Iowa, Iowa City, Iowa;, Departments of Psychology and Physiology, University of Wisconsin, Madison, Wisconsin; and
Kirill V Nourski - Department of Neurosurgery, University of Iowa, Iowa City, Iowa
Hiroyuki Oya - Department of Neurosurgery, University of Iowa, Iowa City, Iowa
Richard A Reale - Department of Neurosurgery, University of Iowa, Iowa City, Iowa;, Departments of Psychology and Physiology, University of Wisconsin, Madison, Wisconsin; and
Hiroto Kawasaki - Department of Neurosurgery, University of Iowa, Iowa City, Iowa
Mitchell Steinschneider - Departments of Neurology and Neuroscience, Albert Einstein College of Medicine, New York, New York
Matthew A Howard - Department of Neurosurgery, University of Iowa, Iowa City, Iowa
Resource Type: Journal article
Publication Details: Journal of neurophysiology, Vol.102(4), pp.2358-2374
DOI: 10.1152/jn.91346.2008
PMID: 19675285
PMCID: PMC2775384
NLM abbreviation: J Neurophysiol
ISSN: 0022-3077
eISSN: 1522-1598
Language: English
Date published: 10/2009
Academic Unit: Neurology; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
Record Identifier: 9984020749202771

Metrics

22 Record Views

145 Times Cited - Web of Science