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Cognition falters at ~4 Hz in Parkinson’s disease
Journal article   Peer reviewed

Cognition falters at ~4 Hz in Parkinson’s disease

Nandakumar S. Narayanan, Zahra Jourahmad, Rachel C. Cole and James F. Cavanagh
Trends in cognitive sciences, Vol.28(9), pp.789-791
07/12/2024
DOI: 10.1016/j.tics.2024.06.002
PMCID: PMC11458154
PMID: 39003229
url
https://pmc.ncbi.nlm.nih.gov/articles/PMC11458154/pdf/nihms-2003725.pdfView
Open Access

Abstract

Cognitive impairments are common in Parkinson’s disease (PD). We have linked this deficit to attenuated midfrontal 1–8-Hz activity that fails to engage cortical cognitive networks. We discuss the consequences of these impairments and how they might be leveraged for PD-specific neurophysiological markers and for novel brain stimulation paradigms. Cognitive impairments are common in Parkinson’s disease (PD). We have linked this deficit to attenuated midfrontal 1–8-Hz activity that fails to engage cortical cognitive networks. We discuss the consequences of these impairments and how they might be leveraged for PD-specific neurophysiological markers and for novel brain stimulation paradigms.
Dopamine Parkinson’s disease prefrontal cortex

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