Journal article
Cognitive and Neurologic Predictors of Functional Impairment in Vascular Dementia
The American journal of geriatric psychiatry, Vol.11(1), pp.103-106
01/2003
DOI: 10.1097/00019442-200301000-00014
PMID: 12527546
Abstract
The purpose of this study is to investigate associations between executive dysfunction, neuroimaging findings, and functional impairment in patients with vascular dementia (VaD).
Twenty-nine VaD patients completed the Dementia Rating Scale and underwent MRI scanning to generate quantitative ratings of subcortical hyperintensities (SH) and cortical volume. Patients' caregivers completed items from the Lawton and Brody Activities of Daily Living Questionnaire, designed to measure instrumental activities of daily living (IADLs). The authors hypothesized that performance on the Initiation/Perseveration (IP) subscale, a measure of executive abilities, and SH would significantly predict levels of IADLs.
A hierarchical multiple-regression analysis revealed that IP and SH accounted for 42% of the variance in IADLs; IP alone accounted for 28%, and SH accounted for 14% beyond the contribution made by IP.
Findings indicate that specific cognitive and neuropathological factors are associated with functional impairment in VaD.
Details
- Title: Subtitle
- Cognitive and Neurologic Predictors of Functional Impairment in Vascular Dementia
- Creators
- Patricia A Boyle - Department of Psychiatry, Brown Medical School, Providence, RIR Paul - Department of Psychiatry, Brown Medical School, Providence, RID Moser - Department of Psychiatry, University of IowaT Zawacki - Department of Psychiatry, Brown Medical School, Providence, RIN Gordon - Department of Psychiatry, Brown Medical School, Providence, RIR Cohen - Department of Psychiatry, Brown Medical School, Providence, RI
- Resource Type
- Journal article
- Publication Details
- The American journal of geriatric psychiatry, Vol.11(1), pp.103-106
- Publisher
- Elsevier Inc
- DOI
- 10.1097/00019442-200301000-00014
- PMID
- 12527546
- ISSN
- 1064-7481
- eISSN
- 1545-7214
- Language
- English
- Date published
- 01/2003
- Academic Unit
- Psychiatry; Medicine Administration
- Record Identifier
- 9984004196702771
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