Cognitive and daily functioning in older adults with vegetative symptoms of depression

Sergio Paradiso; Kevin Duff; Jatin G Vaidya; Angela Hoth; James W Mold

doi:10.1002/gps.2376

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Cognitive and daily functioning in older adults with vegetative symptoms of depression

Journal article

Open access

Peer reviewed

Cognitive and daily functioning in older adults with vegetative symptoms of depression

Sergio Paradiso, Kevin Duff, Jatin G Vaidya, Angela Hoth and James W Mold

International journal of geriatric psychiatry, Vol.25(6), pp.569-577

06/2010

DOI: 10.1002/gps.2376

PMCID: PMC3789530

PMID: 19806600

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https://www.ncbi.nlm.nih.gov/pmc/articles/3789530View

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Abstract

In primary care 50-95% of patients with depression present with vegetative symptoms (VS). Based on the extant literature, older adults showing VS (but no dysphoria) may show functional impairment but this hypothesis has not been empirically tested. The goal of this study was to examine neurocognitive and daily functioning of elderly patients showing exclusively VS in comparison with patients presenting with VS and dysphoria. Seven hundred and eighty-seven primary care patients received measures of neurocognition and daily functioning. Neurocognition was measured with the repeatable battery for the assessment of neuropsychological status (RBANS). Three groups were compared: (1) patients with two or more VS of depression without dysphoria (VS - D), (2) patients with at least one VS and dysphoria (VS + D), and (3) comparison patients without multiple VS or dysphoria. Nearly one third of the sample (31%) fell into the VS - D group, whereas 15% fell into the VS + D group. Both VS groups showed poorer neurocognition and activities of daily living than comparisons. Only one subtest of the RBANS (i.e., picture naming) showed a significant difference between VS + D and VS - D, and there was no significant difference on daily functioning. VS - D patients reported less frequent past history of depression and endorsed less anxiety compared to VS + D. Elderly patients presenting with clusters of VS with or without dysphoria show poorer neurocognitive and functional performance. Relative poorer cognition and daily functioning in VS - D are potential harbingers of further decline and consistent with under-reporting of sadness in older age.

Humans

Male

Memory Disorders - diagnosis

Sleep Wake Disorders - diagnosis

Fatigue - diagnosis

Activities of Daily Living

Neuropsychological Tests

Cognition Disorders - diagnosis

Psychiatric Status Rating Scales

Aged, 80 and over

Female

Aged

Appetitive Behavior

Depressive Disorder - psychology

Cognition Disorders - epidemiology

Cognition Disorders - psychology

Details

Title: Subtitle: Cognitive and daily functioning in older adults with vegetative symptoms of depression
Creators: Sergio Paradiso - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA. sergio-paradiso@uiowa.edu
Kevin Duff
Jatin G Vaidya
Angela Hoth
James W Mold
Resource Type: Journal article
Publication Details: International journal of geriatric psychiatry, Vol.25(6), pp.569-577
DOI: 10.1002/gps.2376
PMID: 19806600
PMCID: PMC3789530
NLM abbreviation: Int J Geriatr Psychiatry
ISSN: 0885-6230
eISSN: 1099-1166
Publisher: England
Grant note: 5K23AG027837 / NIA NIH HHS K23 AG027837 / NIA NIH HHS
Language: English
Date published: 06/2010
Academic Unit: Psychiatry; Iowa Neuroscience Institute; University College Courses
Record Identifier: 9984003996302771

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