Journal article
Cognitive function, quality of life, and aging: relationships in individuals with and without spinal cord injury
Physiotherapy theory and practice, Vol.38(1), pp.36-45
01/02/2022
DOI: 10.1080/09593985.2020.1712755
PMCID: PMC7702216
PMID: 31914347
Abstract
Background: Correlations between aging, cognitive impairment and poor quality of life (QOL) have been observed for many patient populations.
Objective: The purpose of this study was to examine these correlations in individuals with and without spinal cord injury (SCI).
Methods: 23 individuals with complete SCI and 20 individuals without SCI ("NON") underwent assessment of cognitive function via the NIH Toolbox for Neurological and Behavioral Function. Participants self-rated QOL via global and symptom/domain-specific measures.
Results: SCI rated global QOL to be lower than NON for the EQ-5D QALY (p < .001), but not the EQ-5D VAS, which imposes no penalty for wheeled mobility. Low QOL clustered mainly in domains pertaining to physical function/symptoms. Participants with SCI reported high QOL for positive affect/well-being and resilience. Cognitive function in SCI did not differ from NON. However, strong correlations between age and cognition observed in NON (all R
2
> 0.532) were absent in SCI. Significant correlations between cognition and QOL were prevalent for NON but not for SCI.
Conclusions: Dissociation of age, cognition and QOL occurred with SCI. Divergence between EQ-5D QALY and VAS suggests that individuals with SCI may recalibrate personal assessments of QOL in ways that minimize the importance of mobility impairment.
Details
- Title: Subtitle
- Cognitive function, quality of life, and aging: relationships in individuals with and without spinal cord injury
- Creators
- Shauna Dudley-Javoroski - Roy J. and Lucille A. Carver College of MedicineJinhyun Lee - Roy J. and Lucille A. Carver College of MedicineRichard K. Shields - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Physiotherapy theory and practice, Vol.38(1), pp.36-45
- DOI
- 10.1080/09593985.2020.1712755
- PMID
- 31914347
- PMCID
- PMC7702216
- NLM abbreviation
- Physiother Theory Pract
- ISSN
- 0959-3985
- eISSN
- 1532-5040
- Publisher
- Taylor & Francis
- Grant note
- DOI: 10.13039/100006937, name: National Center for Medical Rehabilitation Research, award: R01 HD082109, R01 HD084645; name: The University of Iowa Institute for Clinical and Translational Science, award: NIH UL1TR002537
- Language
- English
- Date published
- 01/02/2022
- Academic Unit
- Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984295058602771
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