Cognitive predictors of functional decline in vascular dementia

Angela L Jefferson; Deborah Cahn-Weiner; Patricia Boyle; Robert H Paul; David J Moser; Norman Gordon; Ronald A Cohen

doi:10.1002/gps.1556

Back

Cognitive predictors of functional decline in vascular dementia

Journal article

Peer reviewed

Cognitive predictors of functional decline in vascular dementia

Angela L Jefferson, Deborah Cahn-Weiner, Patricia Boyle, Robert H Paul, David J Moser, Norman Gordon and Ronald A Cohen

International journal of geriatric psychiatry, Vol.21(8), pp.752-754

08/2006

DOI: 10.1002/gps.1556

PMCID: PMC2746410

PMID: 16906630

View Online

Abstract

Background: This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. Methods: Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activities of daily living (BADL). Follow-up assessment was conducted one-year post-baseline. Results: Logistic regression revealed that changes in the DRS Initiation/Perseveration and DRS Memory subscales were significantly associated with declines in IADLs and BADLs, respectively. Conclusions: Among patients with VaD, longitudinal changes in IADLs and BADLs are most strongly associated with changes in executive functioning and memory abilities, respectively. Findings suggest that different cognitive functions subserve complex instrumental and rote, habituated basic functional activities, and neuropsychological screening measures are useful in the prediction of such functional changes.

Neuropsychology

functional decline

Dementia Rating Scale (DRS)

activities of daily living (ADLs)

memory

cognition

vascular dementia (VaD)

executive function

Details

Title: Subtitle: Cognitive predictors of functional decline in vascular dementia
Creators: Angela L Jefferson - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
Deborah Cahn-Weiner - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
Patricia Boyle - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
Robert H Paul - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
David J Moser - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
Norman Gordon - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
Ronald A Cohen - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA
Resource Type: Journal article
Publication Details: International journal of geriatric psychiatry, Vol.21(8), pp.752-754
DOI: 10.1002/gps.1556
PMID: 16906630
PMCID: PMC2746410
NLM abbreviation: Int J Geriatr Psychiatry
ISSN: 0885-6230
eISSN: 1099-1166
Publisher: Wiley
Language: English
Date published: 08/2006
Academic Unit: Psychiatry; Medicine Administration
Record Identifier: 9984003401102771

Metrics

20 Record Views

35 Times Cited - Web of Science