Journal article
Coinfection alters the playing field: herpesviruses induce acyclovir to inhibit HIV
Cell host & microbe, Vol.4(3), pp.194-195
09/11/2008
DOI: 10.1016/j.chom.2008.08.006
PMID: 18779044
Abstract
The antiherpes drug acyclovir was found to inhibit HIV following its phosphorylation by human herpesviruses, providing a hypothesis to explain the observed beneficial effects of acyclovir therapy on HIV viral load and HIV disease progression. This report underscores the importance of studying HIV in the context of microbial copathogens.
Details
- Title: Subtitle
- Coinfection alters the playing field: herpesviruses induce acyclovir to inhibit HIV
- Creators
- Jack T Stapleton - Department of Internal Medicine, The University of Iowa and Iowa City VA Medical Center, SW54, GH, 200 Hawkins Drive, Iowa City, IA 52242, USA. jack-stapleton@uiowa.eduHenry H Balfour Jr
- Resource Type
- Journal article
- Publication Details
- Cell host & microbe, Vol.4(3), pp.194-195
- DOI
- 10.1016/j.chom.2008.08.006
- PMID
- 18779044
- ISSN
- 1931-3128
- eISSN
- 1934-6069
- Language
- English
- Date published
- 09/11/2008
- Academic Unit
- Microbiology and Immunology; Infectious Diseases; Internal Medicine
- Record Identifier
- 9984094760902771
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