Colorectal cancer screening adherence is higher with fecal immunochemical tests than guaiac-based fecal occult blood tests: A randomized, controlled trial

Richard M Hoffman; Susan Steel; Ellen F.T Yee; Larry Massie; Ronald M Schrader; Glen H Murata

doi:10.1016/j.ypmed.2010.03.010

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Colorectal cancer screening adherence is higher with fecal immunochemical tests than guaiac-based fecal occult blood tests: A randomized, controlled trial

Journal article

Peer reviewed

Colorectal cancer screening adherence is higher with fecal immunochemical tests than guaiac-based fecal occult blood tests: A randomized, controlled trial

Richard M Hoffman, Susan Steel, Ellen F.T Yee, Larry Massie, Ronald M Schrader and Glen H Murata

Preventive medicine, Vol.50(5), pp.297-299

2010

DOI: 10.1016/j.ypmed.2010.03.010

PMID: 20307568

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Abstract

Determine whether colorectal cancer screening adherence is greater with fecal immunochemical tests (FIT) or guaiac-based fecal occult blood tests (gFOBT). We used electronic health records to identify 3869 New Mexico Veterans Affairs Health Care System primary care patients due for screening in 2008 for whom fecal blood testing was appropriate. We invited randomly selected patients by mail to participate in a study comparing FIT and gFOBT. We randomly allocated 404 subjects to receive FIT ( n = 202) or gFOBT ( n = 202) by mail. We determined the proportion of subjects completing testing within 90 days of agreeing to participate in the study. We also used multivariate logistic regression to evaluate screening completion, adjusting for age, gender, race/ethnicity, clinic site, previous gFOBT testing, and co-morbidity. Screening adherence was higher with FIT than gFOBT (61.4% vs. 50.5%, P = 0.03). The adjusted odds ratio for completing FIT vs. gFOBT was 1.56, 95% CI 1.04, 2.32. In a clinic setting of patients who were due for colorectal cancer screening, adherence was significantly higher with FIT than gFOBT.

Medical records systems, computerized

Early detection of cancer

Colorectal neoplasms

Occult blood

Randomized controlled trial

Patient compliance

Details

Title: Subtitle: Colorectal cancer screening adherence is higher with fecal immunochemical tests than guaiac-based fecal occult blood tests: A randomized, controlled trial
Creators: Richard M Hoffman - Medicine Service, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
Susan Steel - Medicine Service, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
Ellen F.T Yee - Medicine Service, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
Larry Massie - Laboratory Service, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
Ronald M Schrader - University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
Glen H Murata - Medicine Service, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
Resource Type: Journal article
Publication Details: Preventive medicine, Vol.50(5), pp.297-299
DOI: 10.1016/j.ypmed.2010.03.010
PMID: 20307568
NLM abbreviation: Prev Med
ISSN: 0091-7435
eISSN: 1096-0260
Publisher: Elsevier Inc
Language: English
Date published: 2010
Academic Unit: Epidemiology; General Internal Medicine; Internal Medicine
Record Identifier: 9984094376402771

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