Journal article
Commentary: Indefensible Methods of Handling Missing Data in Clinical Trials
Alcoholism, clinical and experimental research, Vol.37(12), pp.1997-1998
12/2013
DOI: 10.1111/acer.12294
PMID: 24138458
Abstract
BackgroundLiterature continues to appear using inappropriate statistical methods when dealing with missing data in treatment trials. I regularly see last observation carried forward, assumed worst-case scenario, or some other static imputation method still being submitted and published in journals.
MethodsWe briefly cover a few reasons why the use of more modern and defensible methods may not have completely saturated the literature.
ResultsWhile some delay in complete permeation of appropriate methods is understandable, we are currently past the point for reasonable delay.
ConclusionsEditors and reviewers should demand appropriate statistical methods in published literature.
Details
- Title: Subtitle
- Commentary: Indefensible Methods of Handling Missing Data in Clinical Trials
- Creators
- Stephan Arndt - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Alcoholism, clinical and experimental research, Vol.37(12), pp.1997-1998
- DOI
- 10.1111/acer.12294
- PMID
- 24138458
- NLM abbreviation
- Alcohol Clin Exp Res
- ISSN
- 0145-6008
- eISSN
- 1530-0277
- Publisher
- Wiley
- Number of pages
- 2
- Language
- English
- Date published
- 12/2013
- Academic Unit
- Psychiatry; Biostatistics; Nursing; Injury Prevention Research Center
- Record Identifier
- 9985132071202771
Metrics
1 Record Views