Journal article
Committee Opinion No. 675 Summary: Management of Vulvar Intraepithelial Neoplasia
Obstetrics and gynecology (New York. 1953), Vol.128(4), pp.937-938
10/01/2016
DOI: 10.1097/AOG.0000000000001704
PMID: 27661648
Abstract
Vulvar intraepithelial neoplasia (VIN) is an increasingly common problem, particularly among women in their 40s. Although spontaneous regression has been reported, VIN should be considered a premalignant condition. Immunization with the quadrivalent or 9-valent human papillomavirus vaccine, which is effective against human papillomavirus genotypes 6, 11, 16, and 18, and 6, 11, 16, 18, 31, 33, 45, 52, and 58, respectively, has been shown to decrease the risk of vulvar high-grade squamous intraepithelial lesion (HSIL) (VIN usual type) and should be recommended for girls aged 11-12 years with catch-up through age 26 years if not vaccinated in the target age. There are no screening strategies for the prevention of vulvar cancer through early detection of vulvar HSIL (VIN usual type). Detection is limited to visual assessment with confirmation by histopathology when needed. Treatment is recommended for all women with vulvar HSIL (VIN usual type). Because of the potential for occult invasion, wide local excision should be performed if cancer is suspected, even if biopsies show vulvar HSIL. When occult invasion is not a concern, vulvar HSIL (VIN usual type) can be treated with excision, laser ablation, or topical imiquimod (off-label use). Given the relatively slow rate of progression, women with a complete response to therapy and no new lesions at follow-up visits scheduled 6 months and 12 months after initial treatment should be monitored by visual inspection of the vulva annually thereafter.
Details
- Title: Subtitle
- Committee Opinion No. 675 Summary: Management of Vulvar Intraepithelial Neoplasia
- Creators
- Committee on Gynecologic Practice American Society for Colposcopy and Cervical Pathology
- Contributors
- Colleen Stockdale (Contributor) - University of Iowa, Obstetrics and GynecologyOluwatosin Goje (Contributor)Jason Reutter (Contributor)Herschel Lawson (Contributor) - National Center for Chronic Disease Prevention and Health Promotion
- Resource Type
- Journal article
- Publication Details
- Obstetrics and gynecology (New York. 1953), Vol.128(4), pp.937-938
- Publisher
- Lippincott Williams & Wilkins, WK Health
- DOI
- 10.1097/AOG.0000000000001704
- PMID
- 27661648
- ISSN
- 0029-7844
- eISSN
- 1873-233X
- Language
- English
- Date published
- 10/01/2016
- Description audience
- Academic
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984318322702771
Metrics
5 Record Views