Journal article
Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: an analysis of the US Nationwide inpatient sample
BMC cardiovascular disorders, Vol.14, 73
06/05/2014
DOI: 10.1186/1471-2261-14-73
PMCID: PMC4057902
PMID: 24898986
Abstract
Background: Treatment of heart failure (HF) is particularly complex in the presence of comorbidities. We sought to identify and associate comorbidity profiles with inpatient outcomes during HF hospitalizations.
Methods: Latent mixture modeling was used to identify common profiles of comorbidities during adult hospitalizations for HF from the 2009 Nationwide Inpatient Sample (n = 192,327).
Results: Most discharges were characterized by "common" comorbidities. A "lifestyle" profile was characterized by a high prevalence of uncomplicated diabetes, hypertension, chronic pulmonary disorders and obesity. A "renal" profile had the highest prevalence of renal disease, complicated diabetes, and fluid and electrolyte imbalances. A "neurovascular" profile represented the highest prevalence of cerebrovascular disease, paralysis, myocardial infarction and peripheral vascular disease. Relative to the common profile, the lifestyle profile was associated with a 15% longer length of stay (LOS) and 12% greater cost, the renal profile was associated with a 30% higher risk of death, 27% longer LOS and 24% greater cost, and the neurovascular profile was associated with a 45% higher risk of death, 34% longer LOS and 37% greater cost (all p < 0.001).
Conclusions: Comorbidity profiles are helpful in identifying adults at higher risk of death, longer length of stay, and accumulating greater costs during hospitalizations for HF.
Details
- Title: Subtitle
- Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: an analysis of the US Nationwide inpatient sample
- Creators
- Christopher S. Lee - Oregon Health & Science UniversityChristopher V. Chien - Oregon Health & Science UniversityJulie T. Bidwell - Oregon Health & Science UniversityJill M. Gelow - Oregon Health & Science UniversityQuin E. Denfeld - Oregon Health & Science UniversityRuth Masterson Creber - University of PennsylvaniaHarleah G. Buck - Pennsylvania State UniversityJames O. Mudd - Oregon Health & Science University
- Resource Type
- Journal article
- Publication Details
- BMC cardiovascular disorders, Vol.14, 73
- DOI
- 10.1186/1471-2261-14-73
- PMID
- 24898986
- PMCID
- PMC4057902
- NLM abbreviation
- BMC Cardiovasc Disord
- ISSN
- 1471-2261
- eISSN
- 1471-2261
- Publisher
- Springer Nature
- Number of pages
- 9
- Grant note
- HD043488-08 / National Institute of Child Health and Human Development through the Oregon Building Interdisciplinary Research on Women's Health program K12HD043488 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) Office of Research on Women's Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Office of Research on Women's Health (ORWH)
- Language
- English
- Date published
- 06/05/2014
- Academic Unit
- Nursing
- Record Identifier
- 9984370647902771
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