Journal article
Comparative Analysis of Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Activity in Serum and Lethality in Mice and Rabbits Pretreated with the Staphylococcal Superantigen Toxic Shock Syndrome Toxin 1
Infection and immunity, Vol.69(11), pp.7169-7172
Note
11/2001
DOI: 10.1128/IAI.69.11.7169-7172.2001
PMCID: PMC100117
PMID: 11598096
Abstract
Host susceptibility to lipopolysaccharide (LPS) is correlated with the levels of circulating tumor necrosis factor alpha (TNF-α) that develop in response to circulating LPS. Mice are resistant, relative to rabbits, to the lethal effects of LPS. This study indicates that mice and rabbits are equally sensitive to the lethal effects of circulating TNF-α but that mice are more resistant than rabbits to the induction of circulating TNF-α by LPS.
Details
- Title: Subtitle
- Comparative Analysis of Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Activity in Serum and Lethality in Mice and Rabbits Pretreated with the Staphylococcal Superantigen Toxic Shock Syndrome Toxin 1
- Creators
- Martin M Dinges - Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455Patrick M Schlievert - Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455
- Resource Type
- Journal article
- Publication Details
- Infection and immunity, Vol.69(11), pp.7169-7172
- Series
- Note
- DOI
- 10.1128/IAI.69.11.7169-7172.2001
- PMID
- 11598096
- PMCID
- PMC100117
- NLM abbreviation
- Infect Immun
- ISSN
- 0019-9567
- eISSN
- 1098-5522
- Publisher
- American Society for Microbiology
- Language
- English
- Date published
- 11/2001
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984001217702771
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