Journal article
Comparative effectiveness research in localized prostate cancer treatment
Journal of comparative effectiveness research, Vol.2(6), pp.583-593
11/2013
DOI: 10.2217/cer.13.66
PMID: 24236797
Abstract
Prostate-specific antigen testing has dramatically increased the incidence of localized prostate cancer. Most men with localized cancer attempt curative therapy, usually with surgery or radiation. However, there is uncertainty about whether and how to best treat these cancers. No published controlled trials have directly compared surgery against radiation or either treatment against active surveillance. Given the indolent nature of prostate cancer and the substantial risks of treatment-related harms, the effects of cancer and treatment on quality of life are important patient-centered outcomes. Comparative effectiveness research, using observational cohorts, claims data and simulation models, enables comparisons of treatments that have not been studied in controlled trials and captures real-world outcomes data to better support informed decision-making.
Details
- Title: Subtitle
- Comparative effectiveness research in localized prostate cancer treatment
- Creators
- Richard M Hoffman - Department of Medicine, University of New Mexico, Albuquerque, NM, USA. rhoffman@unm.eduDavid F PensonAnthony L ZietmanMichael J Barry
- Resource Type
- Journal article
- Publication Details
- Journal of comparative effectiveness research, Vol.2(6), pp.583-593
- DOI
- 10.2217/cer.13.66
- PMID
- 24236797
- ISSN
- 2042-6305
- eISSN
- 2042-6313
- Language
- English
- Date published
- 11/2013
- Academic Unit
- Epidemiology; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984094369402771
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