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Comparison of Results Obtained with Amplicor HIV-1 DNA PCR Test Version 1.5 Using 100 versus 500 Microliters of Whole Blood
Journal article   Open access   Peer reviewed

Comparison of Results Obtained with Amplicor HIV-1 DNA PCR Test Version 1.5 Using 100 versus 500 Microliters of Whole Blood

Estelle Piwowar-Manning, Lebah Lugalia, Bosco Kafufu and J. Brooks Jackson
Journal of clinical microbiology, Vol.46(3), pp.1104-1105
03/2008
DOI: 10.1128/JCM.02259-07
PMCID: PMC2268375
PMID: 18199786
url
https://doi.org/10.1128/JCM.02259-07View
Published (Version of record) Open Access

Abstract

The Amplicor HIV-1 DNA PCR assay (Roche Diagnostics, Branchburg, NJ) requires 500 μl of whole blood for a diagnosis of human immunodeficiency virus type 1 (HIV-1) infection, and this amount is often difficult to obtain from infants. A comparison was performed using 100 and 500 μl of whole blood from infants less than 18 months of age. The concordance rate for HIV DNA PCR-negative and -positive samples was 100% for the two different volumes.
Virology

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