Journal article
Comparison of cardiac magnetic resonance imaging and fluorodeoxyglucose positron emission tomography in the assessment of cardiac sarcoidosis: Meta-analysis and systematic review
Journal of nuclear cardiology, Vol.30(4), pp.1574-1587
2023
DOI: 10.1007/s12350-022-03129-8
PMID: 36443587
Abstract
AIM Fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) and cardiac magnetic resonance (CMR) are frequently used advanced cardiac imaging to diagnose cardiac sarcoidosis (CS). We conducted a meta-analysis and systematic review to compare diagnostic parameters of FDG-PET and CMR in the diagnosis of cardiac sarcoidosis (CS). METHODS We searched PubMed, EMBASE, and Scopus databases from their inception to 9/30/2021 with search terms "cardiac sarcoidosis" AND "cardiac magnetic resonance imaging" AND "positronemission tomography". We extracted patient characteristics, results of the FDG-PET and CMR, and adverse outcomes from the included studies. Adverse outcomes served as a reference standard for the evaluation of FDG-PET and CMR. RESULTS We included 4 studies in the meta-analysis which provided adverse outcomes and all patients underwent FDG-PET and CMR. There were 237 patients, 60.3% male, and ages ranged from 50-53 years. There were 45 events in 237 patients from four studies included in the meta-analyses. The pooled sensitivity (95% confidence interval-CI) and specificity (CI) of CMR in predicting an adverse event were 0.94 (0.79-0.98) and 0.49 (0.40-0.59), respectively. The pooled sensitivity (CI) and specificity (CI) of FDG-PET in predicting an adverse event were 0.51 (0.26-0.75) and 0.60 (0.35-0.81), respectively. CONCLUSION CMR was more sensitive but less specific than FDG-PET in predicting adverse events; however, the study population and definition of a positive test need to be considered while interpreting the results.
Details
- Title: Subtitle
- Comparison of cardiac magnetic resonance imaging and fluorodeoxyglucose positron emission tomography in the assessment of cardiac sarcoidosis: Meta-analysis and systematic review
- Creators
- Mehul AdhadukBishow PaudelMuhammad Umar KhalidMahi AshwathShareef MansourKan Liu
- Resource Type
- Journal article
- Publication Details
- Journal of nuclear cardiology, Vol.30(4), pp.1574-1587
- DOI
- 10.1007/s12350-022-03129-8
- PMID
- 36443587
- ISSN
- 1071-3581
- eISSN
- 1532-6551
- Language
- English
- Electronic publication date
- 11/28/2022
- Date published
- 2023
- Academic Unit
- Radiology; Cardiovascular Medicine; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984322741202771
Metrics
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