Journal article
Comparison of labial minor salivary gland biopsies from childhood Sjögren syndrome and age-matched controls
Journal of rheumatology, Vol.41(6), pp.1178-1182
06/2014
DOI: 10.3899/jrheum.131511
PMID: 24786923
Abstract
To determine an appropriate focus score cutoff for childhood Sjögren syndrome (SS).
Labial salivary gland tissue from specimens from children with SS and age-matched controls was retrospectively identified and reviewed by a blinded oral pathologist.
The presence of any focal sialadenitis (focus score > 0 foci/4 mm(2)) was common among childhood SS samples but present in only 1 of 8 control samples.
The presence of any focal lymphocytic sialadenitis in minor labial salivary gland tissue is suggestive of childhood SS and should be included in future childhood SS-specific diagnostic or classification criteria.
Details
- Title: Subtitle
- Comparison of labial minor salivary gland biopsies from childhood Sjögren syndrome and age-matched controls
- Creators
- Naoto Yokogawa - From the Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Department of Dermatology, Division of Dermatopathology, and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine, Columbus, Ohio; Division of Anatomic Pathology, and the Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.N. Yokogawa, MD, Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center; S.M. Lieberman, MD, PhD, Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa; F. Alawi, DDS, Department of Dermatology, Division of Dermatopathology, University of Pennsylvania; S. Bout-Tabaku, MD, MSc, Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine; M. Guttenberg, MD, Division of Anatomic Pathology; D.D. Sherry, MD, Division of Rheumatology, The Children's Hospital of Philadelphia; F.B. Vivino, MD, MS, Division of Rheumatology, University of PennsylvaniaScott M Lieberman - University of Iowa, Stead Family Department of PediatricsFaizan Alawi - From the Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Department of Dermatology, Division of Dermatopathology, and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine, Columbus, Ohio; Division of Anatomic Pathology, and the Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.N. Yokogawa, MD, Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center; S.M. Lieberman, MD, PhD, Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa; F. Alawi, DDS, Department of Dermatology, Division of Dermatopathology, University of Pennsylvania; S. Bout-Tabaku, MD, MSc, Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine; M. Guttenberg, MD, Division of Anatomic Pathology; D.D. Sherry, MD, Division of Rheumatology, The Children's Hospital of Philadelphia; F.B. Vivino, MD, MS, Division of Rheumatology, University of PennsylvaniaSharon Bout-Tabaku - From the Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Department of Dermatology, Division of Dermatopathology, and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine, Columbus, Ohio; Division of Anatomic Pathology, and the Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.N. Yokogawa, MD, Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center; S.M. Lieberman, MD, PhD, Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa; F. Alawi, DDS, Department of Dermatology, Division of Dermatopathology, University of Pennsylvania; S. Bout-Tabaku, MD, MSc, Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine; M. Guttenberg, MD, Division of Anatomic Pathology; D.D. Sherry, MD, Division of Rheumatology, The Children's Hospital of Philadelphia; F.B. Vivino, MD, MS, Division of Rheumatology, University of PennsylvaniaMarta Guttenberg - From the Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Department of Dermatology, Division of Dermatopathology, and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine, Columbus, Ohio; Division of Anatomic Pathology, and the Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.N. Yokogawa, MD, Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center; S.M. Lieberman, MD, PhD, Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa; F. Alawi, DDS, Department of Dermatology, Division of Dermatopathology, University of Pennsylvania; S. Bout-Tabaku, MD, MSc, Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine; M. Guttenberg, MD, Division of Anatomic Pathology; D.D. Sherry, MD, Division of Rheumatology, The Children's Hospital of Philadelphia; F.B. Vivino, MD, MS, Division of Rheumatology, University of PennsylvaniaDavid D Sherry - From the Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Department of Dermatology, Division of Dermatopathology, and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine, Columbus, Ohio; Division of Anatomic Pathology, and the Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.N. Yokogawa, MD, Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center; S.M. Lieberman, MD, PhD, Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa; F. Alawi, DDS, Department of Dermatology, Division of Dermatopathology, University of Pennsylvania; S. Bout-Tabaku, MD, MSc, Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine; M. Guttenberg, MD, Division of Anatomic Pathology; D.D. Sherry, MD, Division of Rheumatology, The Children's Hospital of Philadelphia; F.B. Vivino, MD, MS, Division of Rheumatology, University of PennsylvaniaFrederick B Vivino - From the Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Department of Dermatology, Division of Dermatopathology, and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine, Columbus, Ohio; Division of Anatomic Pathology, and the Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.N. Yokogawa, MD, Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center; S.M. Lieberman, MD, PhD, Stead Family Department of Pediatrics, Division of Rheumatology, Carver College of Medicine, University of Iowa; F. Alawi, DDS, Department of Dermatology, Division of Dermatopathology, University of Pennsylvania; S. Bout-Tabaku, MD, MSc, Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, Ohio State University College of Medicine; M. Guttenberg, MD, Division of Anatomic Pathology; D.D. Sherry, MD, Division of Rheumatology, The Children's Hospital of Philadelphia; F.B. Vivino, MD, MS, Division of Rheumatology, University of Pennsylvania
- Resource Type
- Journal article
- Publication Details
- Journal of rheumatology, Vol.41(6), pp.1178-1182
- DOI
- 10.3899/jrheum.131511
- PMID
- 24786923
- NLM abbreviation
- J Rheumatol
- ISSN
- 0315-162X
- eISSN
- 1499-2752
- Language
- English
- Date published
- 06/2014
- Academic Unit
- Stead Family Department of Pediatrics; Rheumatology, Allergy, and Immunology
- Record Identifier
- 9984093218102771
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