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Comparison of the analytic sensitivities of a recombinant immunoblot assay and the radioimmune precipitation assay for the detection of antibodies to Trypanosoma cruzi in patients with Chagas disease
Journal article   Peer reviewed

Comparison of the analytic sensitivities of a recombinant immunoblot assay and the radioimmune precipitation assay for the detection of antibodies to Trypanosoma cruzi in patients with Chagas disease

Dinesh O. Shah, Chi-Deu Chang, Kevin Y. Cheng, Vince A. Salbilla, Neeraj Adya, Benedict A. Marchlewicz and Louis V. Kirchhoff
Diagnostic microbiology and infectious disease, Vol.67(4), pp.402-405
08/01/2010
DOI: 10.1016/j.diagmicrobio.2010.03.013
PMID: 20638614

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Abstract

The diagnosis of chronic Chagas disease usually is made by detecting antibodies to Trypanosoma cruzi, the protozoan parasite that causes this illness. A highly sensitive and specific immunoblot assay developed by us showed a higher analytic sensitivity than the radioimmune precipitation assay, which is used widely as a confirmatory test. (C) 2010 Elsevier Inc. All rights reserved.
Infectious Diseases Life Sciences & Biomedicine Microbiology Science & Technology

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