Journal article
Comparison of tibiofemoral joint space width measurements from standing CT and fixed flexion radiography
Journal of orthopaedic research, Vol.35(7), pp.1388-1395
07/2017
DOI: 10.1002/jor.23387
PMCID: PMC5299055
PMID: 27504863
Abstract
The objective of this project was to determine the relationship between medial tibiofemoral joint space width measured on fixed-flexion radiographs and the three-dimensional joint space width distribution on low-dose, standing CT (SCT) imaging. At the 84-month visit of the Multicenter Osteoarthritis Study, 20 participants were recruited. A commercial SCT scanner for the foot and ankle was modified to image knees while standing. Medial tibiofemoral joint space width was assessed on radiographs at fixed locations from 15% to 30% of compartment width using validated software and on SCT by mapping the distances between three-dimensional subchondral bone surfaces. Individual joint space width values from radiographs were compared with three-dimensional joint space width values from corresponding sagittal plane locations using paired t-tests and correlation coefficients. For the four medial-most tibiofemoral locations, radiographic joint space width values exceeded the minimal joint space width on SCT by a mean of 2.0 mm and were approximately equal to the 61st percentile value of the joint space width distribution at each respective sagittal-plane location. Correlation coefficients at these locations were 0.91-0.97 and the offsets between joint space width values from radiographs and SCT measurements were consistent. There were greater offsets and variability in the offsets between modalities closer to the tibial spine. Joint space width measurements on fixed-flexion radiographs are highly correlated with three-dimensional joint space width from SCT. In addition to avoiding bony overlap obscuring the joint, a limitation of radiographs, the current study supports a role for SCT in the evaluation of tibiofemoral OA. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1388-1395, 2017.
Details
- Title: Subtitle
- Comparison of tibiofemoral joint space width measurements from standing CT and fixed flexion radiography
- Creators
- Neil A Segal - Department of Epidemiology, The University of Iowa College of Public Health, Iowa City, IowaEric Frick - Department of Orthopaedics and Rehabilitation, The University of Iowa, Iowa City, IowaJeffrey Duryea - Brigham and Women's Hospital/Harvard Medical School, Boston, MassachusettsMichael C Nevitt - Department of Epidemiology and Biostatistics, University of California, San Francisco, CaliforniaJingbo Niu - Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MassachusettsJames C Torner - Department of Epidemiology, The University of Iowa College of Public Health, Iowa City, IowaDavid T Felson - Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MassachusettsDonald D Anderson - Department of Orthopaedics and Rehabilitation, The University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of orthopaedic research, Vol.35(7), pp.1388-1395
- DOI
- 10.1002/jor.23387
- PMID
- 27504863
- PMCID
- PMC5299055
- NLM abbreviation
- J Orthop Res
- ISSN
- 1554-527X
- eISSN
- 1554-527X
- Publisher
- United States
- Grant note
- U01 AG018832 / NIA NIH HHS U01 AG019069 / NIA NIH HHS U01 AG018820 / NIA NIH HHS
- Language
- English
- Date published
- 07/2017
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Iowa Technology Institute; Epidemiology; Orthopedics and Rehabilitation; Surgery; Industrial and Systems Engineering; Injury Prevention Research Center; Neurosurgery
- Record Identifier
- 9983995056302771
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