Journal article
Complete ophthalmoplegia: an unusual sign of bilateral paramedian midbrain-thalamic infarction
Stroke (1970), Vol.39(4), pp.1355-1357
04/2008
DOI: 10.1161/STROKEAHA.107.504761
PMID: 18309144
Abstract
Complete ophthalmoplegia, the combination of bilateral ptosis with loss of all extraocular movements, is rarely a consequence of ischemic stroke. We describe 3 patients who had complete ophthalmoplegia as a manifestation of bilateral paramedian midbrain-thalamic infarction, and we discuss possible pathophysiologic mechanisms. Summary of Cases- Three patients presented with coma. All had complete ophthalmoplegia that initially persisted despite improvement or fluctuation in their other deficits. MRI revealed bilateral paramedian midbrain-thalamic infarction. Two patients died, with the ophthalmoplegia remaining unchanged before death. The surviving patient had a progressive improvement in ocular abduction but persisting third nerve and vertical gaze palsies. Complete ophthalmoplegia is an unusual sign of bilateral paramedian midbrain-thalamic infarction. The ophthalmoplegia could result from combined third nerve, pseudoabducens, and vertical gaze palsies.
Details
- Title: Subtitle
- Complete ophthalmoplegia: an unusual sign of bilateral paramedian midbrain-thalamic infarction
- Creators
- Matthew J Thurtell - Department of Neurology, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Australia. matthewt@icn.usyd.edu.auG Michael Halmagyi
- Resource Type
- Journal article
- Publication Details
- Stroke (1970), Vol.39(4), pp.1355-1357
- Publisher
- United States
- DOI
- 10.1161/STROKEAHA.107.504761
- PMID
- 18309144
- ISSN
- 0039-2499
- eISSN
- 1524-4628
- Language
- English
- Date published
- 04/2008
- Academic Unit
- Neurology; Ophthalmology and Visual Sciences
- Record Identifier
- 9983979908102771
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