Journal article
Complete separation of four potassium currents in drosophila
Neuron (Cambridge, Mass.), Vol.2(4), pp.1325-1329
1989
DOI: 10.1016/0896-6273(89)90070-6
PMID: 2516727
Abstract
A number of voltage-activated and Ca
2+ activated K
+ currents are known to coexist and play a major role in a wide variety of cellular processes including neuromuscular phenomena. Separation of these currents is important for analyzing their individual functional roles and for understanding whether or not they are mediated by entirely different channels. In Drosophila, we have now been able to manipulate four different K
+ currents, individually and in combination with one another, by a combined use of mutations and pharmacological agents. This allows analysis of the physiological and molecular properties of different K
+ channels and of the role of individual currents in membrane excitability.
Details
- Title: Subtitle
- Complete separation of four potassium currents in drosophila
- Creators
- Satpal SinghChun-Fang Wu
- Resource Type
- Journal article
- Publication Details
- Neuron (Cambridge, Mass.), Vol.2(4), pp.1325-1329
- DOI
- 10.1016/0896-6273(89)90070-6
- PMID
- 2516727
- NLM abbreviation
- Neuron
- ISSN
- 0896-6273
- eISSN
- 1097-4199
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1989
- Academic Unit
- Iowa Neuroscience Institute; Biology
- Record Identifier
- 9984070847902771
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