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Complex Segregation Analysis of Gilles-De-La-Tourette Syndrome - further Evidence for a Major Locus Mode of Transmission
Journal article   Peer reviewed

Complex Segregation Analysis of Gilles-De-La-Tourette Syndrome - further Evidence for a Major Locus Mode of Transmission

Eric J. Devor
American Journal of Human Genetics, Vol.36(3), pp.704-709
01/01/1984

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Abstract

A sample of 35 published pedigrees of Gilles de la Tourette syndrome is studied using complex segregation analysis with pointers. Results indicate the presence of a rare, semidominant, incompletely penetrant allele leading to affection. This result is consistent with that previously reported by Comings et al. on a larger, independent sample.
Obstetrics and Gynecology

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