Journal article
Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study
Anaesthesia, Vol.77(6), pp.649-658
06/2022
DOI: 10.1111/anae.15716
PMCID: PMC9111470
PMID: 35319088
Abstract
Respiratory adverse events in adults with COVID-19 undergoing general anaesthesia can be life-threatening. However, there remains a knowledge gap about respiratory adverse events in children with COVID-19. We created an international observational registry to collect airway management outcomes in children with COVID-19 who were having a general anaesthetic. We hypothesised that children with confirmed or suspected COVID-19 would experience more hypoxaemia and complications than those without. Between 3 April 2020 and 1 November 2020, 78 international centres participated. In phase 1, centres collected outcomes on all children (age <= 18 y) having a general anaesthetic for 2 consecutive weeks. In phase 2, centres recorded outcomes for children with test-confirmed or suspected COVID-19 (based on symptoms) having a general anaesthetic. We did not study children whose tracheas were already intubated. The primary outcome was the incidence of hypoxaemia during airway management. Secondary outcomes included: incidence of other complications; and first-pass success rate for tracheal intubation. In total, 7896 children were analysed (7567 COVID-19 negative and 329 confirmed or presumed COVID-19 positive). The incidence of hypoxaemia during airway management was greater in children who were COVID-19 positive (24 out of 329 (7%) vs. 214 out of 7567 (3%); OR 2.70 (95%CI 1.70-4.10)). Children who had symptoms of COVID-19 had a higher incidence of hypoxaemia compared with those who were asymptomatic (9 out of 51 (19%) vs. 14 out of 258 (5%), respectively; OR 3.7 (95%CI 1.5-9.1)). Children with confirmed or presumed COVID-19 have an increased risk of hypoxaemia during airway management in conjunction with general anaesthesia.
Details
- Title: Subtitle
- Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study
- Creators
- M. Brooks Peterson - Children's Hospital ColoradoH. G. Gurnaney - Children's Hospital of PhiladelphiaN. Disma - Istituto Giannina GasliniC. Matava - Hospital for Sick ChildrenN. Jagannathan - Lurie Children's HospitalM. L. Stein - Boston Children's HospitalH. Liu - Children's Hospital of PhiladelphiaP. G. Kovatsis - Boston Children's HospitalB. S. Von Ungern-Sternberg - Univ Western Australia, Perth Childrens Hosp, Telethon Kids Inst, Dept Anesthesia & Pain Med, Perth, WA, AustraliaJ. E. Fiadjoe - University of PennsylvaniaPediatric AirWay complicationS during COVID-19 (PAWS-COVID-19) GroupPatrick N Olomu (Contributor) - Anesthesia
- Resource Type
- Journal article
- Publication Details
- Anaesthesia, Vol.77(6), pp.649-658
- Publisher
- Wiley
- DOI
- 10.1111/anae.15716
- PMID
- 35319088
- PMCID
- PMC9111470
- ISSN
- 0003-2409
- eISSN
- 1365-2044
- Number of pages
- 10
- Grant note
- Anesthesia Patient Safety Foundation Children's Hospital of Philadelphia Department of Anesthesiology and Critical Care Medicine
- Language
- English
- Date published
- 06/2022
- Academic Unit
- Anesthesia
- Record Identifier
- 9984656606702771
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